Detalhe da pesquisa
1.
Prevention and treatment of SHIVAD8 infection in rhesus macaques by a potent d-peptide HIV entry inhibitor.
Proc Natl Acad Sci U S A
; 117(36): 22436-22442, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32820072
2.
Traceless Click-Assisted Native Chemical Ligation Enabled by Protecting Dibenzocyclooctyne from Acid-Mediated Rearrangement with Copper(I).
Bioconjug Chem
; 32(10): 2233-2244, 2021 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34619957
3.
A glutamic acid-based traceless linker to address challenging chemical protein syntheses.
Org Biomol Chem
; 19(40): 8821-8829, 2021 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34585207
4.
Characterization of resistance to a potent D-peptide HIV entry inhibitor.
Retrovirology
; 16(1): 28, 2019 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31640718
5.
Synthesis of hydrophobic insulin-based peptides using a helping hand strategy.
Org Biomol Chem
; 17(7): 1703-1708, 2019 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29947407
6.
Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag.
Org Biomol Chem
; 17(48): 10237-10244, 2019 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31793605
7.
Pharmacokinetic and Chemical Synthesis Optimization of a Potent d-Peptide HIV Entry Inhibitor Suitable for Extended-Release Delivery.
Mol Pharm
; 15(3): 1169-1179, 2018 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29436835
8.
Aligator: A computational tool for optimizing total chemical synthesis of large proteins.
Bioorg Med Chem
; 25(18): 4946-4952, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28651912
9.
Synthesis and folding of a mirror-image enzyme reveals ambidextrous chaperone activity.
Proc Natl Acad Sci U S A
; 111(32): 11679-84, 2014 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25071217
10.
A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis.
J Am Chem Soc
; 138(36): 11775-82, 2016 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27532670
11.
Synthesis of tumor necrosis factor α for use as a mirror-image phage display target.
Org Biomol Chem
; 14(23): 5298-303, 2016 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27211891
12.
Virion stiffness regulates immature HIV-1 entry.
Retrovirology
; 10: 4, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23305456
13.
Novel preclinical models of topical PrEP pharmacodynamics provide rationale for combination of drugs with complementary properties.
Retrovirology
; 10: 113, 2013 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24156604
14.
Corrigendum: Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial sepsis by inhibiting neutrophil extracellular traps.
Front Immunol
; 14: 1171222, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37063850
15.
A synthetic delivery vector for mucosal vaccination.
Biomaterials
; 302: 122298, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37713762
16.
One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates.
J Virol
; 85(15): 7582-93, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593172
17.
Design of a modular tetrameric scaffold for the synthesis of membrane-localized D-peptide inhibitors of HIV-1 entry.
Bioconjug Chem
; 23(6): 1252-8, 2012 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22545664
18.
Improved Handling of Peptide Segments Using Side Chain-Based "Helping Hand" Solubilizing Tools.
Methods Mol Biol
; 2530: 81-107, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35761044
19.
Homogeneous surrogate virus neutralization assay to rapidly assess neutralization activity of anti-SARS-CoV-2 antibodies.
Nat Commun
; 13(1): 3716, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778399
20.
Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial sepsis by inhibiting neutrophil extracellular traps.
Front Immunol
; 13: 1046574, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36733389