Detalhe da pesquisa
1.
Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing.
Proc Natl Acad Sci U S A
; 114(32): E6490-E6497, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739942
2.
Rapid changes in the microvascular circulation of skeletal muscle impair insulin delivery during sepsis.
Am J Physiol Endocrinol Metab
; 316(6): E1012-E1023, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30860883
3.
Amphiphilic Polyelectrolyte Graft Copolymers Enhance the Activity of Cyclic Dinucleotide STING Agonists.
Adv Healthc Mater
; 10(2): e2001056, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33225632
4.
Genetically Encoded Split-Luciferase Biosensors to Measure Endosome Disruption Rapidly in Live Cells.
ACS Sens
; 5(7): 1929-1936, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32573202
5.
Endosomolytic and Tumor-Penetrating Mesoporous Silica Nanoparticles for siRNA/miRNA Combination Cancer Therapy.
ACS Appl Mater Interfaces
; 12(4): 4308-4322, 2020 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31939276
6.
Modifying Cell Membranes with Anionic Polymer Amphiphiles Potentiates Intracellular Delivery of Cationic Peptides.
ACS Appl Mater Interfaces
; 12(45): 50222-50235, 2020 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33124813
7.
Microparticle Depots for Controlled and Sustained Release of Endosomolytic Nanoparticles.
Cell Mol Bioeng
; 12(5): 429-442, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31719925
8.
Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability.
ACS Nano
; 13(2): 1136-1152, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30629431
9.
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
Nat Commun
; 10(1): 5012, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31676764
10.
Excipients for the lyoprotection of MAPKAP kinase 2 inhibitory peptide nano-polyplexes.
J Control Release
; 282: 110-119, 2018 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29709529
11.
Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Cancer Res
; 78(7): 1845-1858, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358172
12.
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.
ACS Nano
; 11(6): 5680-5696, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28548843
13.
Mechanism of Enhanced Cellular Uptake and Cytosolic Retention of MK2 Inhibitory Peptide Nano-polyplexes.
Cell Mol Bioeng
; 9(3): 368-381, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818713
14.
Hydrolytic charge-reversal of PEGylated polyplexes enhances intracellular un-packaging and activity of siRNA.
J Biomed Mater Res A
; 104(4): 917-27, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26691570
15.
Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti-MicroRNA Therapies.
Adv Mater
; 28(36): 7984-7992, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27383910
16.
Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles.
J Biomed Mater Res A
; 103(9): 3107-16, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25641816
17.
Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers.
Biomaterials
; 38: 97-107, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453977
18.
MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia.
Sci Transl Med
; 7(291): 291ra95, 2015 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26062847
19.
Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction.
ACS Nano
; 9(6): 5893-907, 2015 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26004140
20.
Thiol-acrylate nanocomposite foams for critical size bone defect repair: A novel biomaterial.
J Biomed Mater Res A
; 101(12): 3531-41, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629851