Detalhe da pesquisa
1.
HAP40 protein levels are huntingtin-dependent and decrease in Huntington disease.
Neurobiol Dis
; 158: 105476, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390835
2.
Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation.
Biochim Biophys Acta
; 1862(9): 1558-69, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27240544
3.
Linear and extended: a common polyglutamine conformation recognized by the three antibodies MW1, 1C2 and 3B5H10.
Hum Mol Genet
; 22(20): 4215-23, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23777629
4.
The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation.
Brain
; 137(Pt 2): 411-9, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24369382
5.
Huntingtin affinity for partners is not changed by polyglutamine length: aggregation itself triggers aberrant interactions.
Hum Mol Genet
; 20(14): 2795-806, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21518730
6.
Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to induce neutralizing antibodies in old mice.
Front Immunol
; 14: 1231274, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37753087
7.
Mutation spectrum in the large GTPase dynamin 2, and genotype-phenotype correlation in autosomal dominant centronuclear myopathy.
Hum Mutat
; 33(6): 949-59, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22396310
8.
Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease.
J Huntingtons Dis
; 11(3): 227-242, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35871360
9.
Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient.
J Mol Biol
; 371(1): 235-44, 2007 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17560603
10.
SynAggreg: A Multifunctional High-Throughput Technology for Precision Study of Amyloid Aggregation and Systematic Discovery of Synergistic Inhibitor Compounds.
J Mol Biol
; 430(24): 5257-5279, 2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30266595
11.
Structure of a single-chain Fv bound to the 17 N-terminal residues of huntingtin provides insights into pathogenic amyloid formation and suppression.
J Mol Biol
; 427(12): 2166-78, 2015 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25861763
12.
Biochemical and NMR mapping of the interface between CREB-binding protein and ligand binding domains of nuclear receptor: beyond the LXXLL motif.
J Biol Chem
; 280(7): 5682-92, 2005 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15542861
13.
Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.
Hum Mol Genet
; 13(12): 1257-65, 2004 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115762