Detalhe da pesquisa
1.
Altered blood gene expression in the obesity-related type 2 diabetes cluster may be causally involved in lipid metabolism: a Mendelian randomisation study.
Diabetologia
; 66(6): 1057-1070, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36826505
2.
Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses.
J Lipid Res
; 63(5): 100193, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35278410
3.
Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.
Diabetologia
; 64(1): 260-261, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184701
4.
The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.
Diabetologia
; 63(4): 744-756, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32002573
5.
Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts.
PLoS Med
; 17(6): e1003149, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32559194
6.
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium.
Diabetologia
; 62(9): 1601-1615, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31203377
7.
Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes.
Diabetes Obes Metab
; 19(3): 356-363, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27862873
8.
Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.
PLoS Genet
; 10(6): e1004388, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24922540
9.
Innate biology versus lifestyle behaviour in the aetiology of obesity and type 2 diabetes: the GLACIER Study.
Diabetologia
; 59(3): 462-71, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26625858
10.
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry.
PLoS Genet
; 9(7): e1003607, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935507
11.
Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.
Diabetologia
; 58(5): 997-1005, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25707907
12.
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium.
Diabetologia
; 57(6): 1132-42, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24695864
13.
Precision prognostics for cardiovascular disease in Type 2 diabetes: a systematic review and meta-analysis.
Commun Med (Lond)
; 4(1): 11, 2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253823
14.
The association of cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI DIRECT study.
J Clin Endocrinol Metab
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38686701
15.
Exercise and diabetes-related cardiovascular disease: systematic review of published evidence from observational studies and clinical trials.
Curr Diab Rep
; 13(3): 372-80, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23494754
16.
Polygenic risk in Type III hyperlipidaemia and risk of cardiovascular disease: An epidemiological study in UK Biobank and Oxford Biobank.
Int J Cardiol
; 373: 72-78, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410544
17.
Precision Prognostics for Cardiovascular Disease in Type 2 Diabetes: A Systematic Review and Meta-analysis.
medRxiv
; 2023 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37162891
18.
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits.
Nat Commun
; 14(1): 5062, 2023 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37604891
19.
Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.
Nat Biotechnol
; 41(3): 399-408, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36593394
20.
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study.
Cell Rep Med
; 3(1): 100477, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35106505