Detalhe da pesquisa
1.
Prevention of Respiratory Syncytial Virus Infection in Healthy Adults by a Single Immunization of Ad26.RSV.preF in a Human Challenge Study.
J Infect Dis
; 226(3): 396-406, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33400792
2.
The effective rate of influenza reassortment is limited during human infection.
PLoS Pathog
; 13(2): e1006203, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28170438
3.
Activity of Oral ALS-008176 in a Respiratory Syncytial Virus Challenge Study.
N Engl J Med
; 373(21): 2048-58, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26580997
4.
The human viral challenge model: accelerating the evaluation of respiratory antivirals, vaccines and novel diagnostics.
Respir Res
; 19(1): 123, 2018 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29929556
5.
Phase 2 Randomized Trial of the Safety and Efficacy of MHAA4549A, a Broadly Neutralizing Monoclonal Antibody, in a Human Influenza A Virus Challenge Model.
Antimicrob Agents Chemother
; 61(11)2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28807912
6.
Virus-specific antibody secreting cell, memory B-cell, and sero-antibody responses in the human influenza challenge model.
J Infect Dis
; 209(9): 1354-61, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24415790
7.
Reply to Hunsberger and Memoli, "Efficacy Analysis in Healthy-Volunteer Influenza Challenge Trials: Intention To Treat".
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269431
8.
Use of a human influenza challenge model to assess person-to-person transmission: proof-of-concept study.
J Infect Dis
; 205(1): 35-43, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22131338
9.
Inhibition of viral and bacterial trigger-stimulated prostaglandin E2 by a throat lozenge containing flurbiprofen: An in vitro study using a human respiratory epithelial cell line.
SAGE Open Med
; 8: 2050312120960568, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33029351
10.
A COVID-19 human viral challenge model. Learning from experience.
Influenza Other Respir Viruses
; 14(6): 747-756, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32790065
11.
The manufacturing of human viral challenge agents for use in clinical studies to accelerate the drug development process.
BMC Res Notes
; 11(1): 620, 2018 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157933
12.
Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model.
PLoS One
; 11(1): e0145902, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26761707
13.
A Tool for Investigating Asthma and COPD Exacerbations: A Newly Manufactured and Well Characterised GMP Wild-Type Human Rhinovirus for Use in the Human Viral Challenge Model.
PLoS One
; 11(12): e0166113, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27936016
14.
An Intranasal Proteosome-Adjuvanted Trivalent Influenza Vaccine Is Safe, Immunogenic & Efficacious in the Human Viral Influenza Challenge Model. Serum IgG & Mucosal IgA Are Important Correlates of Protection against Illness Associated with Infection.
PLoS One
; 11(12): e0163089, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28005959
15.
Correction: Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model.
PLoS One
; 11(6): e0157211, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27280602
16.
A Synthetic Influenza Virus Vaccine Induces a Cellular Immune Response That Correlates with Reduction in Symptomatology and Virus Shedding in a Randomized Phase Ib Live-Virus Challenge in Humans.
Clin Vaccine Immunol
; 22(7): 828-35, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25994549
17.
Use of qualitative integrative cycler PCR (qicPCR) to identify optimal therapeutic dosing time-points in a Respiratory Syncytial Virus Human Viral Challenge Model (hVCM).
J Virol Methods
; 224: 83-90, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26335961
18.
Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge.
PLoS One
; 9(5): e93761, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24850536
19.
Correlation between human leukocyte antigen class II alleles and HAI titers detected post-influenza vaccination.
PLoS One
; 8(8): e71376, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23951151
20.
Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans.
Nat Med
; 18(2): 274-80, 2012 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22286307