Detalhe da pesquisa
1.
Anxiety, depression, and memory loss in Chagas disease: a puzzle far beyond neuroinflammation to be unpicked and solved.
Mem Inst Oswaldo Cruz
; 118: e220287, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37018799
2.
Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity against Trypanosoma cruzi In Vitro and In Vivo.
Antimicrob Agents Chemother
; 66(11): e0028422, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36314800
3.
Multi-therapeutic strategy targeting parasite and inflammation-related alterations to improve prognosis of chronic Chagas cardiomyopathy: a hypothesis-based approach.
Mem Inst Oswaldo Cruz
; 117: e220019, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320825
4.
Increased angiogenesis parallels cardiac tissue remodelling in experimental acute Trypanosoma cruzi infection.
Mem Inst Oswaldo Cruz
; 117: e220005, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36417626
5.
Resveratrol Reverses Functional Chagas Heart Disease in Mice.
PLoS Pathog
; 12(10): e1005947, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27788262
6.
Single nucleotide polymorphisms of cytokine-related genes and association with clinical outcome in a Chagas disease case-control study from Brazil.
Mem Inst Oswaldo Cruz
; 113(6): e170489, 2018 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29768622
7.
Priming astrocytes with TNF enhances their susceptibility to Trypanosoma cruzi infection and creates a self-sustaining inflammatory milieu.
J Neuroinflammation
; 14(1): 182, 2017 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877735
8.
A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy.
PLoS Pathog
; 11(1): e1004594, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25617628
9.
Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease.
Antimicrob Agents Chemother
; 60(7): 4297-309, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27161638
10.
Behavioural alterations are independent of sickness behaviour in chronic experimental Chagas disease.
Mem Inst Oswaldo Cruz
; 110(8): 1042-50, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26676323
11.
CD8+ T-cells expressing interferon gamma or perforin play antagonistic roles in heart injury in experimental Trypanosoma cruzi-elicited cardiomyopathy.
PLoS Pathog
; 8(4): e1002645, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22532799
12.
Levels of circulating anti-muscarinic and anti-adrenergic antibodies and their effect on cardiac arrhythmias and dysautonomia in murine models of Chagas disease.
Parasitology
; 141(13): 1769-78, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25093253
13.
Tumor necrosis factor is a therapeutic target for immunological unbalance and cardiac abnormalities in chronic experimental Chagas' heart disease.
Mediators Inflamm
; 2014: 798078, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25140115
14.
Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease.
Mem Inst Oswaldo Cruz
; 109(3): 289-98, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24937048
15.
Preclinical evaluation of combined therapy with amiodarone and low-dose benznidazole in a mouse model of chronic Trypanosoma cruzi infection.
Biomed Pharmacother
; 175: 116742, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754265
16.
Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy.
PLoS Negl Trop Dis
; 17(3): e0011223, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972298
17.
Vascular Growth Factor Inhibition with Bevacizumab Improves Cardiac Electrical Alterations and Fibrosis in Experimental Acute Chagas Disease.
Biology (Basel)
; 12(11)2023 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37998013
18.
Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy.
J Clin Med
; 12(8)2023 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37109224
19.
ASP-2/Trans-sialidase chimeric protein induces robust protective immunity in experimental models of Chagas' disease.
NPJ Vaccines
; 8(1): 81, 2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37258518
20.
Mast cell function and death in Trypanosoma cruzi infection.
Am J Pathol
; 179(4): 1894-904, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21819958