Detalhe da pesquisa
1.
Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.
Proc Natl Acad Sci U S A
; 118(15)2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33833060
2.
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
Alzheimers Dement
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38713744
3.
Biophysical characteristics of lipid-induced Aß oligomers correlate to distinctive phenotypes in transgenic mice.
FASEB J
; 35(2): e21318, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33508158
4.
Anti-tau scFvs Targeted to the Cytoplasm or Secretory Pathway Variably Modify Pathology and Neurodegenerative Phenotypes.
Mol Ther
; 29(2): 859-872, 2021 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33128896
5.
Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer's Disease Like Amyloid Pathology in APP-TgCRND8 Mice.
Int J Mol Sci
; 23(6)2022 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35328748
6.
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.
Alzheimers Dement
; 17(6): 984-1004, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33480174
7.
Neurite orientation dispersion and density imaging reveals white matter and hippocampal microstructure changes produced by Interleukin-6 in the TgCRND8 mouse model of amyloidosis.
Neuroimage
; 202: 116138, 2019 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31472250
8.
Holdase activity of secreted Hsp70 masks amyloid-ß42 neurotoxicity in Drosophila.
Proc Natl Acad Sci U S A
; 113(35): E5212-21, 2016 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27531960
9.
Anti-Aß single-chain variable fragment antibodies exert synergistic neuroprotective activities in Drosophila models of Alzheimer's disease.
Hum Mol Genet
; 24(21): 6093-105, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26253732
10.
A human monoclonal IgG that binds aß assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo.
J Neurosci
; 35(16): 6265-76, 2015 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25904780
11.
Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis.
Hippocampus
; 26(4): 455-71, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26418152
12.
IFN-γ promotes τ phosphorylation without affecting mature tangles.
FASEB J
; 29(10): 4384-98, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26156074
13.
Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.
Mol Ther
; 23(1): 53-62, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25228069
14.
Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid.
medRxiv
; 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260316
15.
Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo.
Eur J Neurosci
; 37(8): 1203-20, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23347239
16.
Robust cytoplasmic accumulation of phosphorylated TDP-43 in transgenic models of tauopathy.
Acta Neuropathol
; 126(1): 39-50, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23666556
17.
A C1qTNF3 collagen domain fusion chaperones diverse secreted proteins and anti-Aß scFvs: Applications for gene therapies.
Mol Ther Methods Clin Dev
; 31: 101146, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38027063
18.
Aß Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease.
bioRxiv
; 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38076912
19.
Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aß plaque pathology when injected into newborn mouse hosts.
Free Neuropathol
; 3(9)2022 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35494163
20.
AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model.
EMBO Mol Med
; 14(4): e09824, 2022 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35352880