Detalhe da pesquisa
1.
Dual contribution of ASIC1a channels in the spinal processing of pain information by deep projection neurons revealed by computational modeling.
PLoS Comput Biol
; 19(4): e1010993, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37068087
2.
C-Jun N-Terminal Kinase Post-Translational Regulation of Pain-Related Acid-Sensing Ion Channels 1b and 3.
J Neurosci
; 41(42): 8673-8685, 2021 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34380759
3.
Non-acidic activation of pain-related Acid-Sensing Ion Channel 3 by lipids.
EMBO J
; 35(4): 414-28, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26772186
4.
Black mamba venom peptides target acid-sensing ion channels to abolish pain.
Nature
; 490(7421): 552-5, 2012 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23034652
5.
Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
J Biol Chem
; 291(6): 2616-29, 2016 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26680001
6.
Binding site and inhibitory mechanism of the mambalgin-2 pain-relieving peptide on acid-sensing ion channel 1a.
J Biol Chem
; 289(19): 13363-73, 2014 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24695733
7.
Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions.
Proc Natl Acad Sci U S A
; 109(32): 13124-9, 2012 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22829666
8.
Acid-sensing ion channel 3 mediates pain hypersensitivity associated with high-fat diet consumption in mice.
Pain
; 165(2): 470-486, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37733484
9.
Acid-sensing ion channels in postoperative pain.
J Neurosci
; 31(16): 6059-66, 2011 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21508231
10.
ASIC3, a sensor of acidic and primary inflammatory pain.
EMBO J
; 27(22): 3047-55, 2008 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18923424
11.
Single Subcutaneous Injection of Lysophosphatidyl-Choline Evokes ASIC3-Dependent Increases of Spinal Dorsal Horn Neuron Activity.
Front Mol Neurosci
; 15: 880651, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35774865
12.
Mechanisms of Action of the Peptide Toxins Targeting Human and Rodent Acid-Sensing Ion Channels and Relevance to Their In Vivo Analgesic Effects.
Toxins (Basel)
; 14(10)2022 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36287977
13.
Lysophosphatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3.
Pain
; 163(10): 1999-2013, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35086123
14.
Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat acid-sensing ion channel 1a.
Neuropharmacology
; 185: 108453, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450275
15.
Structural elements for the generation of sustained currents by the acid pain sensor ASIC3.
J Biol Chem
; 284(46): 31851-9, 2009 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19778905
16.
Acid sensing ion channels in dorsal spinal cord neurons.
J Neurosci
; 28(6): 1498-508, 2008 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-18256271
17.
[An ionic channel involved in the skin protection against pressure]. / Un canal ionique qui protège la peau de la pression.
Med Sci (Paris)
; 29(2): 130-2, 2013 Feb.
Artigo
em Francês
| MEDLINE | ID: mdl-23452594
18.
Effects of systemic inhibitors of acid-sensing ion channels 1 (ASIC1) against acute and chronic mechanical allodynia in a rodent model of migraine.
Br J Pharmacol
; 175(21): 4154-4166, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30079481
19.
Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ).
Neuropharmacology
; 125: 429-440, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28802647
20.
Acid-Sensing Ion Channel 1a in the amygdala is involved in pain and anxiety-related behaviours associated with arthritis.
Sci Rep
; 7: 43617, 2017 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28321113