Detalhe da pesquisa
1.
Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures.
Cell
; 180(4): 655-665.e18, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32004463
2.
Crystal Structure of the Human Cannabinoid Receptor CB2.
Cell
; 176(3): 459-467.e13, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639103
3.
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.
Cell
; 172(4): 719-730.e14, 2018 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29398112
4.
Crystal Structure of the Human Cannabinoid Receptor CB1.
Cell
; 167(3): 750-762.e14, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768894
5.
Bitter taste TAS2R14 activation by intracellular tastants and cholesterol.
Nature
; 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38776963
6.
Structural basis of CXC chemokine receptor 2 activation and signalling.
Nature
; 585(7823): 135-140, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610344
7.
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.
Nat Immunol
; 13(12): 1155-61, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142775
8.
NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING.
Immunity
; 40(3): 329-41, 2014 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24560620
9.
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.
Nature
; 546(7657): 312-315, 2017 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28514449
10.
Crystal structures of agonist-bound human cannabinoid receptor CB1.
Nature
; 547(7664): 468-471, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28678776
11.
Ulinastatin inhibits the metastasis of nasopharyngeal carcinoma by involving uPA/uPAR signaling.
Drug Dev Res
; 84(7): 1468-1481, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37534761
12.
A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA.
Genome Res
; 29(2): 193-207, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30670628
13.
Two-Dimensional Detergent Expansion Strategy for Membrane Protein Studies.
Chemistry
; 28(44): e202201388, 2022 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35608006
14.
A Genetically Encoded F-19 NMR Probe Reveals the Allosteric Modulation Mechanism of Cannabinoid Receptor 1.
J Am Chem Soc
; 143(40): 16320-16325, 2021 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34596399
15.
Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding.
Immunity
; 36(6): 1073-86, 2012 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579474
16.
Antioxidants suppress radiation-induced apoptosis via inhibiting MAPK pathway in nasopharyngeal carcinoma cells.
Biochem Biophys Res Commun
; 527(3): 770-777, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446561
17.
Engineering oleaginous yeast Yarrowia lipolytica for enhanced limonene production from xylose and lignocellulosic hydrolysate.
FEMS Yeast Res
; 20(6)2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32840573
18.
Quercetin induces apoptosis and enhances gemcitabine therapeutic efficacy against gemcitabine-resistant cancer cells.
Anticancer Drugs
; 31(7): 684-692, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32282368
19.
Metabolic engineering of ß-carotene biosynthesis in Yarrowia lipolytica.
Biotechnol Lett
; 42(6): 945-956, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32090297
20.
Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist.
Mol Pharmacol
; 96(5): 619-628, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515283