Detalhe da pesquisa
1.
Sodium channel ß1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis.
J Biol Chem
; 295(30): 10380-10393, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32503841
2.
Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons.
Brain
; 143(10): 3025-3040, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32968789
3.
Neuronal hyperexcitability in a mouse model of SCN8A epileptic encephalopathy.
Proc Natl Acad Sci U S A
; 114(9): 2383-2388, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193882
4.
Cardiac arrhythmia in a mouse model of sodium channel SCN8A epileptic encephalopathy.
Proc Natl Acad Sci U S A
; 113(45): 12838-12843, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791149
5.
Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism.
Ann Neurol
; 74(1): 128-39, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23821540
6.
Voltage-gated Na+ channel ß1B: a secreted cell adhesion molecule involved in human epilepsy.
J Neurosci
; 31(41): 14577-91, 2011 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21994374
7.
Na+ channel Scn1b gene regulates dorsal root ganglion nociceptor excitability in vivo.
J Biol Chem
; 286(26): 22913-23, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21555511
8.
Neonatal Scn1b-null mice have sinoatrial node dysfunction, altered atrial structure, and atrial fibrillation.
JCI Insight
; 7(10)2022 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35603785
9.
Sodium channel ß1 subunits participate in regulated intramembrane proteolysis-excitation coupling.
JCI Insight
; 6(3)2021 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33411695
10.
A functional null mutation of SCN1B in a patient with Dravet syndrome.
J Neurosci
; 29(34): 10764-78, 2009 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19710327
11.
Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52.
Ann Clin Transl Neurol
; 7(11): 2137-2149, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32979291
12.
SCN1B-linked early infantile developmental and epileptic encephalopathy.
Ann Clin Transl Neurol
; 6(12): 2354-2367, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31709768
13.
Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain.
J Neurosci
; 26(30): 7984-94, 2006 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16870743
14.
Eating 'Junk-Food' Produces Rapid and Long-Lasting Increases in NAc CP-AMPA Receptors: Implications for Enhanced Cue-Induced Motivation and Food Addiction.
Neuropsychopharmacology
; 41(13): 2977-2986, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27383008
15.
Cannabinoid-induced depression of synaptic transmission is switched to stimulation when dopaminergic tone is increased in the globus pallidus of the rodent.
Neuropharmacology
; 110(Pt A): 407-418, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27506997
16.
Scn2b Deletion in Mice Results in Ventricular and Atrial Arrhythmias.
Circ Arrhythm Electrophysiol
; 9(12)2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27932425
17.
Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.
J Mol Cell Cardiol
; 43(5): 636-47, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17884088