Detalhe da pesquisa
1.
Combined cytotoxic and immune-stimulatory gene therapy using Ad-TK and Ad-Flt3L: Translational developments from rodents to glioma patients.
Mol Ther
; 31(10): 2839-2860, 2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37574780
2.
Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Lancet Oncol
; 24(9): 1042-1052, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657463
3.
Self-organization in brain tumors: How cell morphology and cell density influence glioma pattern formation.
PLoS Comput Biol
; 16(5): e1007611, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32379821
4.
Three recent breakthroughs in CAR T cells for the treatment of glioblastoma: Is it the light at the end of the tunnel?
Mol Ther
; 32(5): 1187-1189, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38631354
5.
Hemispherical Pediatric High-Grade Glioma: Molecular Basis and Therapeutic Opportunities.
Int J Mol Sci
; 21(24)2020 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33348922
6.
Combined cytotoxic and immune-stimulatory gene therapy for glioma - Authors' reply.
Lancet Oncol
; 24(12): e456, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38039998
7.
Evolutionary basis of a new gene- and immune-therapeutic approach for the treatment of malignant brain tumors: from mice to clinical trials for glioma patients.
Clin Immunol
; 189: 43-51, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28720549
8.
Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy.
Clin Immunol
; 189: 34-42, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27777083
9.
Matrix Metalloproteinase Activity in Infections by an Encephalitic Virus, Mouse Adenovirus Type 1.
J Virol
; 91(6)2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28053109
10.
Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy.
Mol Ther
; 25(1): 232-248, 2017 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129117
11.
Cytotoxic immunological synapses do not restrict the action of interferon-γ to antigenic target cells.
Proc Natl Acad Sci U S A
; 109(20): 7835-40, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22547816
12.
Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy.
J Pharmacol Exp Ther
; 349(3): 458-69, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24696041
13.
Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly Pathways.
Adv Sci (Weinh)
; 11(18): e2309796, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38384234
14.
Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation.
bioRxiv
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38559270
15.
A road map for the treatment of pediatric diffuse midline glioma.
Cancer Cell
; 42(1): 1-5, 2024 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38039965
16.
Safety profile, efficacy, and biodistribution of a bicistronic high-capacity adenovirus vector encoding a combined immunostimulation and cytotoxic gene therapy as a prelude to a phase I clinical trial for glioblastoma.
Toxicol Appl Pharmacol
; 268(3): 318-30, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403069
17.
Immune-mediated loss of transgene expression from virally transduced brain cells is irreversible, mediated by IFNγ, perforin, and TNFα, and due to the elimination of transduced cells.
Mol Ther
; 20(4): 808-19, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22233583
18.
Exogenous fms-like tyrosine kinase 3 ligand overrides brain immune privilege and facilitates recognition of a neo-antigen without causing autoimmune neuropathology.
Proc Natl Acad Sci U S A
; 107(32): 14443-8, 2010 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660723
19.
Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics.
Proc Natl Acad Sci U S A
; 107(46): 20021-6, 2010 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21030678
20.
Scale-free correlations and potential criticality in weakly ordered populations of brain cancer cells.
Sci Adv
; 9(26): eadf7170, 2023 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379380