Detalhe da pesquisa
1.
Integrating in Silico and in Vitro Approaches To Predict Drug Accessibility to the Central Nervous System.
Mol Pharm
; 13(5): 1540-50, 2016 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27015243
2.
QSAR workbench: automating QSAR modeling to drive compound design.
J Comput Aided Mol Des
; 27(4): 321-36, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23615761
3.
Lead optimization using matched molecular pairs: inclusion of contextual information for enhanced prediction of HERG inhibition, solubility, and lipophilicity.
J Chem Inf Model
; 50(10): 1872-86, 2010 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20873842
4.
Using Physicochemical Measurements to Influence Better Compound Design.
SLAS Discov
; 24(8): 791-801, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31429385
5.
Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
J Med Chem
; 59(15): 7239-51, 2016 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27429068
6.
On the mechanism of human intestinal absorption.
Eur J Med Chem
; 37(7): 595-605, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12126778
7.
Getting physical in drug discovery II: the impact of chromatographic hydrophobicity measurements and aromaticity.
Drug Discov Today
; 16(17-18): 822-30, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21704184
8.
Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
J Med Chem
; 59(20): 9574, 2016 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27726364
9.
Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.
J Med Chem
; 59(17): 8148, 2016 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27548024
10.
Analysis of the calculated physicochemical properties of respiratory drugs: can we design for inhaled drugs yet?
J Chem Inf Model
; 49(4): 1025-32, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19275169