Detalhe da pesquisa
1.
Inhibition of phosphodiesterase 2 augments cGMP and cAMP signaling to ameliorate pulmonary hypertension.
Circulation
; 130(6): 496-507, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899690
2.
Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase.
Circulation
; 125(23): 2922-32, 2012 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22572914
3.
Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials.
Br J Clin Pharmacol
; 76(5): 649-67, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23351090
4.
Vasoactive peptides and the pathogenesis of pulmonary hypertension: role and potential therapeutic application.
Handb Exp Pharmacol
; 218: 477-511, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24092352
5.
Remote ischemic preconditioning protects the brain against injury after hypothermic circulatory arrest.
Circulation
; 123(7): 714-21, 2011 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300953
6.
Postconditioning protects against human endothelial ischaemia-reperfusion injury via subtype-specific KATP channel activation and is mimicked by inhibition of the mitochondrial permeability transition pore.
Eur Heart J
; 32(10): 1266-74, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21362704
7.
Role of NADPH oxidase in endothelial ischemia/reperfusion injury in humans.
Circulation
; 121(21): 2310-6, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20479156
8.
Synergy between natriuretic peptides and phosphodiesterase 5 inhibitors ameliorates pulmonary arterial hypertension.
Am J Respir Crit Care Med
; 178(8): 861-9, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18689467
9.
Improving the odds of drug development success through human genomics: modelling study.
Sci Rep
; 9(1): 18911, 2019 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31827124
10.
Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial.
Br J Pharmacol
; 176(9): 1251-1267, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30761523
11.
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Circulation
; 116(12): 1386-95, 2007 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17724264
12.
Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trial.
Lancet
; 370(9587): 575-9, 2007 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17707752
13.
(6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm.
Arterioscler Thromb Vasc Biol
; 27(6): 1334-9, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17413035
14.
Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm.
Circulation
; 113(7): 1015-9, 2006 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16476844
15.
Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability.
Circulation
; 111(12): 1530-6, 2005 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-15795363
16.
Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis.
Lancet
; 366(9502): 2026-33, 2005 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-16338452
17.
Remote ischemic preconditioning provides early and late protection against endothelial ischemia-reperfusion injury in humans: role of the autonomic nervous system.
J Am Coll Cardiol
; 46(3): 450-6, 2005 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16053957
18.
High doses of vitamin C reverse Escherichia coli endotoxin-induced hyporeactivity to acetylcholine in the human forearm.
Circulation
; 106(12): 1460-4, 2002 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12234948
19.
Prevention of inflammation-induced endothelial dysfunction: a novel vasculo-protective action of aspirin.
Circulation
; 105(22): 2600-4, 2002 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12045164
20.
Inflammation-induced vasoconstrictor hyporeactivity is caused by oxidative stress.
J Am Coll Cardiol
; 42(9): 1656-62, 2003 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-14607455