Detalhe da pesquisa
1.
Surface salt bridges contribute to the extreme thermal stability of an FN3-like domain from a thermophilic bacterium.
Proteins
; 90(1): 270-281, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34405904
2.
Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.
Proteins
; 84(4): 427-34, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26800003
3.
Induced conformational change in human IL-4 upon binding of a signal-neutralizing DARPin.
Proteins
; 83(6): 1191-7, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25900776
4.
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
Methods
; 65(1): 114-26, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23872058
5.
Structural evidence for a constrained conformation of short CDR-L3 in antibodies.
Proteins
; 82(8): 1679-83, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24470236
6.
Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.
Proteins
; 82(8): 1656-67, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24638881
7.
Antibody modeling assessment II. Structures and models.
Proteins
; 82(8): 1563-82, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24633955
8.
C-terminal ß-strand swapping in a consensus-derived fibronectin Type III scaffold.
Proteins
; 82(7): 1359-69, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24375666
9.
N-terminal ß-strand swapping in a consensus-derived alternative scaffold driven by stabilizing hydrophobic interactions.
Proteins
; 82(7): 1527-33, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464739
10.
Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe
; 31(5): 751-765.e11, 2023 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37098341
11.
Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2.
Sci Immunol
; 7(67): eabk3070, 2022 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793243
12.
Expression, refolding and purification of a human interleukin-17A variant.
Cytokine
; 53(1): 107-14, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20674388
13.
Antigen recognition by antibody C836 through adjustment of V(L)/V(H) packing.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 10): 1165-7, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22102019
14.
Crystallization of a challenging antigen-antibody complex: TLR3 ECD with three noncompeting Fabs.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 10): 1290-5, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22102050
15.
Promoting crystallization of antibody-antigen complexes via microseed matrix screening.
Acta Crystallogr D Biol Crystallogr
; 66(Pt 8): 927-33, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20693692
16.
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
J Alzheimers Dis
; 77(4): 1397-1416, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32894244
17.
Structural insights into humanization of anti-tissue factor antibody 10H10.
MAbs
; 10(2): 269-277, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29283291
18.
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.
J Alzheimers Dis
; 65(1): 265-281, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30040731
19.
Crystal structure of CD27 in complex with a neutralizing noncompeting antibody.
Acta Crystallogr F Struct Biol Commun
; 73(Pt 5): 294-299, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28471362
20.
Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng Des Sel
; 30(1): 31-37, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27881684