Detalhe da pesquisa
1.
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia.
Cell
; 185(13): 2213-2233.e25, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750033
2.
Reply to Peng and Zhao: Loss of endocytic protein TOM1 in Alzheimer's disease.
Proc Natl Acad Sci U S A
; 117(8): 3917-3919, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32047040
3.
Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels.
bioRxiv
; 2023 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711704
4.
Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels.
Commun Biol
; 6(1): 668, 2023 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37355729
5.
Enlarged perivascular spaces and plasma Aß42/Aß40 ratio in older adults without dementia.
Neurobiol Aging
; 128: 43-48, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156179
6.
Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome.
Front Neurosci
; 16: 954999, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36033603
7.
Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome.
Neuron
; 110(13): 2063-2079, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35472307
8.
Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease.
Cell Stem Cell
; 29(7): 1135-1153.e8, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35803230
9.
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice.
Cell Rep
; 39(11): 110961, 2022 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35705056
10.
Aging in Down Syndrome: Latest Clinical Advances and Prospects.
J Clin Med
; 10(21)2021 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34768560
11.
Neuropathology of Aging in Cats and its Similarities to Human Alzheimer's Disease.
Front Aging
; 2: 684607, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35822024
12.
Aging with Down Syndrome-Where Are We Now and Where Are We Going?
J Clin Med
; 10(20)2021 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34682809
13.
SPG302 Reverses Synaptic and Cognitive Deficits Without Altering Amyloid or Tau Pathology in a Transgenic Model of Alzheimer's Disease.
Neurotherapeutics
; 18(4): 2468-2483, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34738197
14.
Generation of a humanized Aß expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Nat Commun
; 12(1): 2421, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33893290
15.
Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome.
Alzheimers Dement (Amst)
; 12(1): e12113, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33088896
16.
miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease.
Aging Cell
; 19(3): e13118, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32087004
17.
Tau underlies synaptic and cognitive deficits for type 1, but not type 2 diabetes mouse models.
Aging Cell
; 18(3): e12919, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30809950
18.
Intra- and extracellular ß-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus.
Sci Rep
; 9(1): 15936, 2019 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685865
19.
Past to Future: What Animal Models Have Taught Us About Alzheimer's Disease.
J Alzheimers Dis
; 64(s1): S365-S378, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29504540
20.
Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease.
Aging Cell
; 17(4): e12791, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29877034