Detalhe da pesquisa
1.
Real-world outcomes of avelumab plus axitinib as first-line therapy in patients with advanced renal cell carcinoma in Japan: A multicenter, retrospective, observational study (J-DART).
Int J Urol
; 31(3): 265-272, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110838
2.
Development and Validation of a Proteomic Correlation Profiling Technique to Detect and Identify Enzymes Involved in Metabolism of Drugs of Concern.
Drug Metab Dispos
; 51(7): 824-832, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156625
3.
Characterization of Enzymes Involved in Nintedanib Metabolism in Humans.
Drug Metab Dispos
; 51(6): 733-742, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927840
4.
Identification of HSD17B12 as an enzyme catalyzing drug reduction reactions through investigation of nabumetone metabolism.
Arch Biochem Biophys
; 736: 109536, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724833
5.
Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10.
J Pharmacol Sci
; 150(1): 41-48, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35926947
6.
In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics.
Drug Metab Dispos
; 49(3): 221-232, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33384384
7.
Quantitative Expression of Hepatobiliary Transporters and Functional Uptake of Substrates in Hepatic Two-Dimensional Sandwich Cultures: A Comparative Evaluation of Upcyte and Primary Human Hepatocytes.
Drug Metab Dispos
; 46(2): 166-177, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29212823
8.
Efficacy and safety of subgroup analysis stratified by baseline HbA1c in a Japanese phase 3 study of dulaglutide 0.75 mg compared with insulin glargine in patients with type 2 diabetes.
Endocr J
; 64(12): 1165-1172, 2017 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28904247
9.
Analysis of efficacy and safety of dulaglutide 0.75 mg stratified by sex in patients with type 2 diabetes in 2 randomized, controlled phase 3 studies in Japan.
Endocr J
; 64(5): 553-560, 2017 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28367916
10.
Pancreatic safety in Japanese patients with type 2 diabetes treated with once weekly dulaglutide 0.75 mg up to 52 weeks in phase 3 clinical trials.
Endocr J
; 64(2): 191-206, 2017 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27853058
11.
Efficacy and safety analyses across 4 subgroups combining low and high age and body mass index groups in Japanese phase 3 studies of dulaglutide 0.75 mg after 26 weeks of treatment.
Endocr J
; 64(4): 449-456, 2017 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28302958
12.
The combination of dulaglutide and biguanide reduced bodyweight in Japanese patients with type 2 diabetes.
Diabetes Obes Metab
; 18(12): 1279-1282, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27488246
13.
One year safety and immunogenicity of AZD1222 (ChAdOx1 nCoV-19): Final analysis of a randomized, placebo-controlled phase 1/2 trial in Japan.
Vaccine
; 41(29): 4199-4205, 2023 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37271703
14.
Immunogenicity and safety of AZD1222 (ChAdOx1 nCoV-19) against SARS-CoV-2 in Japan: a double-blind, randomized controlled phase 1/2 trial.
Int J Infect Dis
; 114: 165-174, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34688944
15.
Subgroup Analysis Stratified by Baseline Pancreatic ß-cell Function in a Japanese Study of Dulaglutide in Patients with Type 2 Diabetes.
Diabetes Ther
; 9(1): 383-394, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29264713
16.
Recent Trends in the Practice of Procedural Sedation Under Local Anesthesia for Catheter Ablation, Gastrointestinal Endoscopy, and Endoscopic Surgery in Japan: A Retrospective Database Study in Clinical Practice from 2012 to 2015.
Drugs Real World Outcomes
; 5(3): 137-147, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-29916196
17.
SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells.
Mutat Res
; 607(1): 88-124, 2006 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-16782396