Detalhe da pesquisa
1.
Nucleosome repositioning in chronic lymphocytic leukemia.
Genome Res
; 33(10): 1649-1661, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37699659
2.
Evaluation of vecabrutinib as a model for noncovalent BTK/ITK inhibition for treatment of chronic lymphocytic leukemia.
Blood
; 139(6): 859-875, 2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662393
3.
Modeling the B-cell receptor signaling on single cell level reveals a stable network circuit topology between nonmalignant B cells and chronic lymphocytic leukemia cells and between untreated cells and cells treated with kinase inhibitors.
Int J Cancer
; 151(5): 783-796, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35527719
4.
Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax.
Blood
; 135(26): 2402-2412, 2020 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32206772
5.
Clonal evolution in chronic lymphocytic leukemia is scant in relapsed but accelerated in refractory cases after chemo(immune) therapy.
Haematologica
; 107(3): 604-614, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33691380
6.
Integrative prognostic models predict long-term survival after immunochemotherapy in chronic lymphocytic leukemia patients.
Haematologica
; 107(3): 615-624, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33730841
7.
HDAC3 functions as a positive regulator in Notch signal transduction.
Nucleic Acids Res
; 48(7): 3496-3512, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32107550
8.
FBXW7 mutations reduce binding of NOTCH1, leading to cleaved NOTCH1 accumulation and target gene activation in CLL.
Blood
; 133(8): 830-839, 2019 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30510140
9.
IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
Blood
; 134(6): 534-547, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31010847
10.
Mutations driving CLL and their evolution in progression and relapse.
Nature
; 526(7574): 525-30, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26466571
11.
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.
Mol Syst Biol
; 15(5): e8339, 2019 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31118277
12.
Prognostic and predictive role of gene mutations in chronic lymphocytic leukemia: results from the pivotal phase III study COMPLEMENT1.
Haematologica
; 105(10): 2440-2447, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054084
13.
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription.
Haematologica
; 105(5): 1379-1390, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31467127
14.
NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.
Int J Cancer
; 142(2): 322-333, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28921505
15.
Triggering T-cell activity in CLL.
Blood
; 137(2): 150-151, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33443561
16.
The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.
J Biol Chem
; 291(42): 22136-22148, 2016 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27542411
17.
Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.
Blood
; 123(21): 3247-54, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24652989
18.
Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.
PLoS Genet
; 9(4): e1003373, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23593011
19.
Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia.
Int J Cancer
; 137(12): 2959-70, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26096065
20.
Loss of cooperativity of secreted CD40L and increased dose-response to IL4 on CLL cell viability correlates with enhanced activation of NF-kB and STAT6.
Int J Cancer
; 136(1): 65-73, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24828787