Detalhe da pesquisa
1.
The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
PLoS Pathog
; 19(12): e1011832, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38039340
2.
PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
FASEB J
; 35(8): e21771, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34275172
3.
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Circ Res
; 126(12): 1723-1745, 2020 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32216531
4.
The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
Genomics
; 113(5): 3128-3140, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34245829
5.
Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
Circulation
; 141(24): 1986-2000, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32192357
6.
An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
FASEB J
; 34(4): 5106-5127, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32068312
7.
Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
FASEB J
; 34(1): 1447-1464, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914641
8.
Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
Circ Res
; 124(12): 1727-1746, 2019 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30922174
9.
von Willebrand Factor Is a Critical Mediator of Deep Vein Thrombosis in a Mouse Model of Diet-Induced Obesity.
Arterioscler Thromb Vasc Biol
; 40(12): 2860-2874, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967458
10.
Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
Arterioscler Thromb Vasc Biol
; 40(11): 2605-2618, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998516
11.
Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
Circulation
; 138(3): 287-304, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29431643
12.
MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
Am J Respir Crit Care Med
; 195(4): 515-529, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27648837
13.
Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2ß1-mediated collagen binding in thrombus formation.
Blood
; 124(11): 1799-807, 2014 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25051961
14.
Maternal hypertension programs increased cerebral tissue damage following stroke in adult offspring.
Mol Cell Biochem
; 408(1-2): 223-33, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26169981
15.
Multiple-site activation of the cysteinyl leukotriene receptor 2 is required for exacerbation of ischemia/reperfusion injury.
Arterioscler Thromb Vasc Biol
; 34(2): 321-30, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24285579
16.
Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function.
J Clin Invest
; 134(11)2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38573824
17.
Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus.
J Am Heart Assoc
; 12(13): e029131, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345832
18.
Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension.
bioRxiv
; 2023 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187628
19.
Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions.
Blood
; 115(23): 4862-9, 2010 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371742
20.
Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
Acta Physiol (Oxf)
; 234(2): e13764, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34978755