Detalhe da pesquisa
1.
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.
Nat Immunol
; 15(3): 231-8, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464131
2.
Sphingosine kinases regulate ER contacts with late endocytic organelles and cholesterol trafficking.
Proc Natl Acad Sci U S A
; 119(39): e2204396119, 2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122218
3.
Neutrophilia in severe asthma is reduced in Ormdl3 overexpressing mice.
FASEB J
; 37(3): e22799, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36753412
4.
Ceramide in apoptosis and oxidative stress in allergic inflammation and asthma.
J Allergy Clin Immunol
; 147(5): 1936-1948.e9, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33130063
5.
Targeting defective sphingosine kinase 1 in Niemann-Pick type C disease with an activator mitigates cholesterol accumulation.
J Biol Chem
; 295(27): 9121-9133, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32385114
6.
Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma.
Handb Exp Pharmacol
; 259: 3-17, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31321542
7.
ORMDL3 and allergic asthma: From physiology to pathology.
J Allergy Clin Immunol
; 144(3): 634-640, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31376405
8.
New insights into functions of the sphingosine-1-phosphate transporter SPNS2.
J Lipid Res
; 60(3): 484-489, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30655317
9.
Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancer.
J Lipid Res
; 59(12): 2297-2307, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30315000
10.
Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking.
J Biol Chem
; 292(8): 3074-3088, 2017 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049734
11.
FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.
FASEB J
; 31(4): 1719-1730, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28082351
12.
Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans.
FASEB J
; 30(8): 2945-58, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27130484
13.
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods.
J Mammary Gland Biol Neoplasia
; 21(1-2): 9-17, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27194029
14.
ORMDL proteins regulate ceramide levels during sterile inflammation.
J Lipid Res
; 57(8): 1412-22, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27313060
15.
Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases.
FASEB J
; 29(12): 5018-28, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324848
16.
Sphingosine-1-phosphate inhibits IL-1-induced expression of C-C motif ligand 5 via c-Fos-dependent suppression of IFN-ß amplification loop.
FASEB J
; 29(12): 4853-65, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26246404
17.
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.
Nature
; 465(7301): 1084-8, 2010 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20577214
18.
The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell-dependent acute allergic responses.
J Allergy Clin Immunol
; 135(4): 1008-1018.e1, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512083
19.
Aberrant ORM (yeast)-like protein isoform 3 (ORMDL3) expression dysregulates ceramide homeostasis in cells and ceramide exacerbates allergic asthma in mice.
J Allergy Clin Immunol
; 136(4): 1035-46.e6, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25842287
20.
Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching.
FASEB J
; 28(10): 4347-58, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25002116