Detalhe da pesquisa
1.
5-Oxo-hexahydroquinoline and 5-oxo-tetrahydrocyclopentapyridine derivatives as promising antiproliferative agents with potential apoptosis-inducing capacity.
Mol Divers
; 26(3): 1481-1500, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671894
2.
5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells.
Toxicol Appl Pharmacol
; 362: 136-149, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30391378
3.
5-Oxo-hexahydroquinoline: an attractive scaffold with diverse biological activities.
Mol Divers
; 23(2): 471-508, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30390186
4.
Synthesis and structure-activity relationship study of multi-target triazine derivatives as innovative candidates for treatment of Alzheimer's disease.
Bioorg Chem
; 77: 223-235, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29367079
5.
Modulation of ERK1/2 and Akt Pathways Involved in the Neurotrophic Action of Caffeic Acid Alkyl Esters.
Molecules
; 23(12)2018 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30562988
6.
Derivatives of caffeic acid, a natural antioxidant, as the basis for the discovery of novel nonpeptidic neurotrophic agents.
Bioorg Med Chem
; 25(12): 3235-3246, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495385
7.
Synthesis and biological evaluation of quinazolinone-based hydrazones with potential use in Alzheimer's disease.
Bioorg Chem
; 74: 126-133, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28780149
8.
Neuroprotective and Antioxidant Activities of 4-Methylcoumarins: Development of Structure-Activity Relationships.
Biol Pharm Bull
; 39(9): 1544-8, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27582333
9.
Structure-based design, synthesis, molecular docking study and biological evaluation of 1,2,4-triazine derivatives acting as COX/15-LOX inhibitors with anti-oxidant activities.
J Enzyme Inhib Med Chem
; 31(6): 1602-11, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27028154
10.
Cytotoxic activity and chemical constituents of Anthemis mirheydari.
Pharm Biol
; 54(10): 2044-9, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864903
11.
Structure-activity relationship studies of 4-methylcoumarin derivatives as anticancer agents.
Pharm Biol
; 54(1): 105-10, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26017566
12.
Synthesis and cytotoxic activity of novel poly-substituted imidazo[2,1-c][1,2,4]triazin-6-amines.
Mol Divers
; 19(2): 273-81, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25613858
13.
N-(2-(Piperazin-1-yl)phenyl)arylamide Derivatives as ß-Secretase (BACE1) Inhibitors: Simple Synthesis by Ugi Four-Component Reaction and Biological Evaluation.
Arch Pharm (Weinheim)
; 348(5): 330-7, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25787800
14.
A validated dispersive liquid-liquid microextraction method for extraction of ochratoxin A from raisin samples.
J Food Sci Technol
; 52(4): 2440-5, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25829630
15.
Cytotoxic, antioxidant and antimicrobial effects of nine species of woundwort (Stachys) plants.
Pharm Biol
; 52(1): 62-7, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24024974
16.
Carthamus, Salvia and Stachys species protect neuronal cells against oxidative stress-induced apoptosis.
Pharm Biol
; 52(12): 1550-7, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25243877
17.
Novel 9-(alkylthio)-Acenaphtho[1,2-e]-1,2,4-triazine derivatives: synthesis, cytotoxic activity and molecular docking studies on B-cell lymphoma 2 (Bcl-2).
Daru
; 22(1): 2, 2014 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24393539
18.
Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives.
BMC Chem
; 18(1): 6, 2024 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184605
19.
Phenylimino-2H-chromen-3-carboxamide derivatives as novel small molecule inhibitors of ß-secretase (BACE1).
Bioorg Med Chem
; 21(8): 2396-2412, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23480856
20.
Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors.
Bioorg Med Chem
; 21(22): 6893-909, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24113238