Detalhe da pesquisa
1.
Dynamic tracing of sugar metabolism reveals the mechanisms of action of synthetic sugar analogs.
Glycobiology
; 32(3): 239-250, 2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34939087
2.
Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state.
Org Biomol Chem
; 15(31): 6656-6667, 2017 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28758655
3.
Bicyclic isoureas derived from 1-deoxynojirimycin are potent inhibitors of ß-glucocerebrosidase.
Org Biomol Chem
; 14(37): 8670-3, 2016 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27604065
4.
Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites.
Org Biomol Chem
; 13(2): 549-60, 2015 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25380215
5.
Unusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: intermolecular bivalent binding.
Biochim Biophys Acta
; 1834(2): 524-35, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23159538
6.
Milk thistle's active components silybin and isosilybin: novel inhibitors of PXR-mediated CYP3A4 induction.
Drug Metab Dispos
; 41(8): 1494-504, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23674609
7.
Immunodominance in mouse and human CD4+ T-cell responses specific for the Bordetella pertussis virulence factor P.69 pertactin.
Infect Immun
; 77(2): 896-903, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19015250
8.
Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3.
Chembiochem
; 10(10): 1724-33, 2009 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19492387
9.
Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT) with Enhanced Activity.
J Med Chem
; 62(14): 6597-6614, 2019 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31265285
10.
Orthoester functionalized N-guanidino derivatives of 1,5-dideoxy-1,5-imino-d-xylitol as pH-responsive inhibitors of ß-glucocerebrosidase.
Medchemcomm
; 8(11): 2050-2054, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30108721
11.
N-Guanidino Derivatives of 1,5-Dideoxy-1,5-imino-d-xylitol are Potent, Selective, and Stable Inhibitors of ß-Glucocerebrosidase.
ChemMedChem
; 12(7): 483-486, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28328014
12.
Limited plasticity in T cell recognition of modified T cell receptor contact residues in MHC class II bound peptides.
Mol Immunol
; 42(3): 355-64, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15589324
13.
Possibilities and limitations in the rational design of modified peptides for T cell mediated immunotherapy.
Mol Immunol
; 42(3): 365-73, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15589325
14.
Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-implications for immunological studies.
Mol Immunol
; 40(13): 943-8, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14725790
15.
Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors.
J Med Chem
; 57(7): 3154-60, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24649802
16.
Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1.
J Med Chem
; 56(3): 1350-4, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23281927
17.
Conformation and intermolecular interactions of SA2 peptides self-assembled into vesicles.
J Phys Chem B
; 114(34): 11046-52, 2010 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-20687533
18.
The role of peptide loops of the Bordetella pertussis protein P.69 pertactin in antibody recognition.
Vaccine
; 25(31): 5902-14, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17597264
19.
Generate: a program for 3-D structure generation and conformational analysis of peptides and peptidomimetics.
J Comput Chem
; 23(7): 746-54, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11948593
20.
Major histocompatibility complex class II binding characteristics of peptoid-peptide hybrids.
Bioorg Med Chem
; 10(6): 1939-45, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-11937352