Detalhe da pesquisa
1.
Over-expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice.
J Cell Mol Med
; 27(15): 2228-2238, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37415307
2.
Exploring the Structural Rearrangements of the Human Insulin-Degrading Enzyme through Molecular Dynamics Simulations.
Int J Mol Sci
; 23(3)2022 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163673
3.
PatchSearch: a web server for off-target protein identification.
Nucleic Acids Res
; 47(W1): W365-W372, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31131411
4.
Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup® Dietary Supplement: Role of Green Tea Catechins.
Int J Mol Sci
; 21(4)2020 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32092951
5.
Four Major Channels Detected in the Cytochrome P450 3A4: A Step toward Understanding Its Multispecificity.
Int J Mol Sci
; 20(4)2019 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30823507
6.
PatchSearch: A Fast Computational Method for Off-Target Detection.
J Chem Inf Model
; 57(4): 769-777, 2017 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28282119
7.
Integrated structure- and ligand-based in silico approach to predict inhibition of cytochrome P450 2D6.
Bioinformatics
; 31(24): 3930-7, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26315915
8.
Design, Synthesis, and Use of MMP-2 Inhibitor-Conjugated Quantum Dots in Functional Biochemical Assays.
Bioconjug Chem
; 27(4): 1067-81, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26930394
9.
PEP-SiteFinder: a tool for the blind identification of peptide binding sites on protein surfaces.
Nucleic Acids Res
; 42(Web Server issue): W221-6, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24803671
10.
Unexpected effect of cyclodepsipeptides bearing a sulfonylhydrazide moiety towards histone deacetylase activity.
Bioorg Chem
; 81: 222-233, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30153587
11.
Comparative Study of the Mutations Observed in the SARS-CoV-2 RBD Variants of Concern and Their Impact on the Interaction with the ACE2 Protein.
J Phys Chem B
; 127(40): 8586-8602, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775095
12.
Catechins as a Potential Dietary Supplementation in Prevention of Comorbidities Linked with Down Syndrome.
Nutrients
; 14(10)2022 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35631180
13.
Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies.
Biomed Pharmacother
; 153: 113372, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35809481
14.
Representations of protein structure for exploring the conformational space: A speed-accuracy trade-off.
Comput Struct Biotechnol J
; 19: 2618-2625, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34025948
15.
SeamDock: An Interactive and Collaborative Online Docking Resource to Assist Small Compound Molecular Docking.
Front Mol Biosci
; 8: 716466, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34604303
16.
An information gain-based approach for evaluating protein structure models.
Comput Struct Biotechnol J
; 18: 2228-2236, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32837711
17.
JNK contributes to Hif-1alpha regulation in hypoxic neurons.
Molecules
; 15(1): 114-27, 2009 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20110876
18.
Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity.
Bioorg Med Chem
; 16(18): 8745-59, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18782669
19.
Class I HDAC Inhibitors: Potential New Epigenetic Therapeutics for Alcohol Use Disorder (AUD).
J Med Chem
; 61(5): 1745-1766, 2018 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28771357
20.
Interest of new alkylsulfonylhydrazide-type compound in the treatment of alcohol use disorders.
Psychopharmacology (Berl)
; 235(6): 1835-1844, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29713786