Detalhe da pesquisa
1.
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.
Cell
; 146(2): 318-31, 2011 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21757228
2.
Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease.
Ann Neurol
; 90(1): 76-88, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33938021
3.
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression.
Nature
; 533(7601): 95-9, 2016 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27096366
4.
A modifier of Huntington's disease onset at the MLH1 locus.
Hum Mol Genet
; 26(19): 3859-3867, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934397
5.
Sequence-Level Analysis of the Major European Huntington Disease Haplotype.
Am J Hum Genet
; 97(3): 435-44, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26320893
6.
Evaluation of logistic regression models and effect of covariates for case-control study in RNA-Seq analysis.
BMC Bioinformatics
; 18(1): 91, 2017 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28166718
7.
Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains.
Hum Mol Genet
; 24(5): 1441-56, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25480889
8.
MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.
PLoS Genet
; 10(2): e1004188, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24586208
9.
Novel microRNA discovery using small RNA sequencing in post-mortem human brain.
BMC Genomics
; 17(1): 776, 2016 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27716130
10.
Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region.
Am J Hum Genet
; 90(3): 434-44, 2012 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22387017
11.
Study of plasma-derived miRNAs mimic differences in Huntington's disease brain.
Mov Disord
; 30(14): 1961-4, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26573701
12.
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons.
PLoS Biol
; 10(11): e1001427, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23185133
13.
Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation.
PLoS Genet
; 8(6): e1002794, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22761592
14.
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
PLoS Genet
; 8(3): e1002548, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22438815
15.
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.
bioRxiv
; 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38496508
16.
Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset.
Neurogenetics
; 14(3-4): 173-9, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23644918
17.
Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study.
PLoS Med
; 10(6): e1001462, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23750121
18.
Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study.
Hum Mol Genet
; 20(8): 1478-87, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21258085
19.
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
Ann Neurol
; 71(3): 370-84, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22451204
20.
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
Am J Respir Crit Care Med
; 186(7): 622-32, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22837378