Detalhe da pesquisa
1.
Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
Nature
; 579(7798): 284-290, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32103175
2.
A Phase I Trial of the VEGF Receptor Tyrosine Kinase Inhibitor Pazopanib in Combination with the MEK Inhibitor Trametinib in Advanced Solid Tumors and Differentiated Thyroid Cancers.
Clin Cancer Res
; 25(18): 5475-5484, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31186313
3.
Cyclin-dependent kinase 5 activity controls cell motility and metastatic potential of prostate cancer cells.
Cancer Res
; 66(15): 7509-15, 2006 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16885348
4.
O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis.
J Clin Invest
; 128(11): 4924-4937, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30130254
5.
Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.
J Clin Endocrinol Metab
; 92(12): 4712-8, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17878251
6.
The Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.
Mol Cell Biol
; 23(2): 543-54, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12509453
7.
Notch signaling induces rapid degradation of achaete-scute homolog 1.
Mol Cell Biol
; 22(9): 3129-39, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11940670
8.
Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer.
J Clin Endocrinol Metab
; 91(1): 79-84, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16263812
9.
Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.
Cancer Res
; 63(11): 2948-56, 2003 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12782602
10.
CEP-701 and CEP-751 inhibit constitutively activated RET tyrosine kinase activity and block medullary thyroid carcinoma cell growth.
Cancer Res
; 63(17): 5559-63, 2003 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14500395
11.
Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling.
J Clin Endocrinol Metab
; 90(7): 4350-6, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15870121
12.
Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models.
Mol Cancer Ther
; 14(7): 1532-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25931518
13.
Trametinib with and without pazopanib has potent preclinical activity in thyroid cancer.
Oncol Rep
; 34(5): 2319-24, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324075
14.
The homeobox gene BARX2 can modulate cisplatin sensitivity in human epithelial ovarian cancer.
Int J Oncol
; 21(5): 929-33, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12370737
15.
Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression.
Oncol Rep
; 32(1): 419-24, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24841903
16.
Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.
J Clin Endocrinol Metab
; 98(2): E364-9, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23264394
17.
Synergistic action of a RAF inhibitor and a dual PI3K/mTOR inhibitor in thyroid cancer.
Clin Cancer Res
; 17(20): 6482-9, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21831957
18.
Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models.
Cancer Biol Ther
; 12(7): 598-609, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21768779
19.
Inhibiting the cyclin-dependent kinase CDK5 blocks pancreatic cancer formation and progression through the suppression of Ras-Ral signaling.
Cancer Res
; 70(11): 4460-9, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20484029
20.
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma.
Cancer Biol Ther
; 10(10): 1009-18, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20818175