Detalhe da pesquisa
1.
C. elegans neurons jettison protein aggregates and mitochondria under neurotoxic stress.
Nature
; 542(7641): 367-371, 2017 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28178240
2.
Some characteristics of crossing over in induced recombination between chromosomes of wheat and rye.
Plant J
; 105(6): 1665-1676, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33346910
3.
Genetic cooperativity in multi-layer networks implicates cell survival and senescence in the striatum of Huntington's disease mice synchronous to symptoms.
Bioinformatics
; 36(1): 186-196, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31228193
4.
Combining feature selection and shape analysis uncovers precise rules for miRNA regulation in Huntington's disease mice.
BMC Bioinformatics
; 21(1): 75, 2020 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32093602
5.
CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington's disease.
Brain
; 142(8): 2432-2450, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31286142
6.
Plasma amyloid ß 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease.
Alzheimers Dement
; 15(6): 764-775, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31113759
7.
AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.
Hum Mol Genet
; 25(6): 1043-58, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26681807
8.
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.
Hum Mol Genet
; 24(12): 3481-96, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25784504
9.
The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.
PLoS Biol
; 12(6): e1001895, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24960609
10.
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.
Nature
; 477(7365): 482-5, 2011 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21938067
11.
Biomarkers of vascular dysfunction and cognitive decline in patients with Alzheimer's disease: no evidence for association in elderly subjects.
Aging Clin Exp Res
; 28(6): 1133-1141, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26803509
12.
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
Proc Natl Acad Sci U S A
; 109(37): 14912-7, 2012 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22927396
13.
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.
Nat Genet
; 37(4): 349-50, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15793589
14.
Integration of ß-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.
J Neurosci
; 32(36): 12630-40, 2012 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22956852
15.
Meclizine is neuroprotective in models of Huntington's disease.
Hum Mol Genet
; 20(2): 294-300, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20977989
16.
SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.
Proc Natl Acad Sci U S A
; 107(17): 7927-32, 2010 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20378838
17.
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia.
Proc Natl Acad Sci U S A
; 107(17): 7863-8, 2010 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385823
18.
Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.
BMC Genomics
; 13: 91, 2012 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22413862
19.
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease.
Neurobiol Dis
; 48(3): 282-9, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22796360
20.
Biosensing Extracellular Vesicle Subpopulations in Neurodegenerative Disease Conditions.
ACS Sens
; 7(6): 1657-1665, 2022 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35446554