Detalhe da pesquisa
1.
Radical S-Adenosyl-l-Methionine Enzyme PylB: A C-Centered Radical to Convert l-Lysine into (3R)-3-Methyl-d-Ornithine.
J Am Chem Soc
; 146(10): 6493-6505, 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38426440
2.
A Versatile Virus-Mimetic Engineering Approach for Concurrent Protein Nanocage Surface-Functionalization and Cargo Encapsulation.
Small
; : e2310913, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38726952
3.
Maturation of the [FeFe]-Hydrogenase: Direct Transfer of the (κ3 -cysteinate)FeII (CN)(CO)2 Complex B from HydG to HydE.
Angew Chem Int Ed Engl
; 62(51): e202314819, 2023 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37962296
4.
Characterization of a Radical SAM Oxygenase for the Ether Crosslinking in Darobactin Biosynthesis.
J Am Chem Soc
; 144(41): 18876-18886, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36194754
5.
Crystal Structure of the [FeFe]-Hydrogenase Maturase HydE Bound to Complex-B.
J Am Chem Soc
; 143(22): 8499-8508, 2021 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34048236
6.
New developments in RiPP discovery, enzymology and engineering.
Nat Prod Rep
; 38(1): 130-239, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32935693
7.
Structural Insights into the Mechanism of the Radical SAM Carbide Synthase NifB, a Key Nitrogenase Cofactor Maturating Enzyme.
J Am Chem Soc
; 142(25): 11006-11012, 2020 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32476412
8.
CO and CN- syntheses by [FeFe]-hydrogenase maturase HydG are catalytically differentiated events.
Proc Natl Acad Sci U S A
; 113(1): 104-9, 2016 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26699472
9.
Radical S-Adenosyl-l-methionine Tryptophan Lyase (NosL): How the Protein Controls the Carboxyl Radical â¢CO2- Migration.
J Am Chem Soc
; 140(48): 16661-16668, 2018 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30418774
10.
1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility.
J Am Chem Soc
; 140(4): 1365-1371, 2018 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29300094
11.
IscS from Archaeoglobus fulgidus has no desulfurase activity but may provide a cysteine ligand for [Fe2S2] cluster assembly.
Biochim Biophys Acta
; 1853(6): 1457-63, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25447670
12.
X-ray snapshots of possible intermediates in the time course of synthesis and degradation of protein-bound Fe4S4 clusters.
Proc Natl Acad Sci U S A
; 110(18): 7188-92, 2013 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23596207
13.
Tryptophan Lyase (NosL): Mechanistic Insights from Substrate Analogues and Mutagenesis.
Biochemistry
; 54(31): 4767-9, 2015 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26204056
14.
Crystal structure of HydG from Carboxydothermus hydrogenoformans: a trifunctional [FeFe]-hydrogenase maturase.
Chembiochem
; 16(3): 397-402, 2015 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25504963
15.
Structure-function relationships of anaerobic gas-processing metalloenzymes.
Nature
; 460(7257): 814-22, 2009 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19675641
16.
Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase.
Biochem J
; 453(3): 393-9, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23679855
17.
Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics.
Proc Natl Acad Sci U S A
; 108(38): 15954-9, 2011 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21896761
18.
Crystal structure of tryptophan lyase (NosL): evidence for radical formation at the amino group of tryptophan.
Angew Chem Int Ed Engl
; 53(44): 11840-4, 2014 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25196319
19.
Structure-function relationships in [FeFe]-hydrogenase active site maturation.
J Biol Chem
; 287(17): 13532-40, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22389497
20.
Genome- and metabolome-guided discovery of marine BamA inhibitors revealed a dedicated darobactin halogenase.
Cell Chem Biol
; 30(8): 943-952.e7, 2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451267