Detalhe da pesquisa
1.
Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells.
Int J Mol Sci
; 22(7)2021 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33810274
2.
Correction: Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.
Org Biomol Chem
; 16(2): 336, 2018 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29256564
3.
Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.
Org Biomol Chem
; 15(40): 8655-8660, 2017 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28984325
4.
PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.
PLoS Genet
; 10(1): e1004004, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24391510
5.
Elaboration of tetra-orthogonally-substituted aromatic scaffolds towards novel EGFR-kinase inhibitors.
Org Biomol Chem
; 14(35): 8246-52, 2016 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27453149
6.
Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis.
Cell Rep
; 43(5): 114224, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38733589
7.
A palmitoyl transferase chemical-genetic system to map ZDHHC-specific S-acylation.
Nat Biotechnol
; 2024 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191663
8.
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade.
Proc Natl Acad Sci U S A
; 106(33): 14132-7, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19666565
9.
Wheat pathogen Zymoseptoria tritici N-myristoyltransferase inhibitors: on-target antifungal activity and an unusual metabolic defense mechanism.
RSC Chem Biol
; 1(2): 68-78, 2020 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34458749
10.
The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling.
Angew Chem Int Ed Engl
; 48(13): 2321-4, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19222062
11.
Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes.
Chem Sci
; 10(39): 8995-9000, 2019 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31762980
12.
Characterization of thyroid hormone receptor alpha (TRalpha)-specific analogs with varying inner- and outer-ring substituents.
Bioorg Med Chem
; 16(2): 762-70, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17988877
13.
Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases.
ACS Chem Biol
; 13(10): 2956-2965, 2018 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30239186
14.
A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding.
Sci STKE
; 2006(341): pl3, 2006 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16804159
15.
A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct.
Oncotarget
; 7(44): 71182-71197, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27563826
16.
A crucial requirement for Hedgehog signaling in small cell lung cancer.
Nat Med
; 17(11): 1504-8, 2011 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21983857
17.
Design and characterization of a thyroid hormone receptor alpha (TRalpha)-specific agonist.
ACS Chem Biol
; 1(9): 585-93, 2006 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17168554
18.
Structure-based design of selective agonists for a rickets-associated mutant of the vitamin d receptor.
J Am Chem Soc
; 124(46): 13795-805, 2002 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12431109