Detalhe da pesquisa
1.
In situ identification of cellular drug targets in mammalian tissue.
Cell
; 185(10): 1793-1805.e17, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483372
2.
Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Mol Cell
; 83(10): 1725-1742.e12, 2023 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084731
3.
Assigning functionality to cysteines by base editing of cancer dependency genes.
Nat Chem Biol
; 19(11): 1320-1330, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783940
4.
Endocannabinoid dysfunction in neurological disease: neuro-ocular DAGLA-related syndrome.
Brain
; 145(10): 3383-3390, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35737950
5.
Chemical Proteomic Discovery of Isotype-Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2.
Angew Chem Int Ed Engl
; 62(51): e202311924, 2023 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37909922
6.
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Nat Chem Biol
; 16(9): 997-1005, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514184
7.
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.
Nat Chem Biol
; 16(6): 667-675, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393901
8.
A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network.
Acta Pharmacol Sin
; 43(11): 3002-3010, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35513432
9.
N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis.
Proc Natl Acad Sci U S A
; 116(49): 24770-24778, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31740614
10.
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
Nat Chem Biol
; 15(5): 453-462, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30911178
11.
Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice.
J Neurosci
; 39(30): 5949-5965, 2019 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127001
12.
ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease.
Biochemistry
; 59(19): 1793-1799, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32364701
13.
Endocannabinoid metabolism and transport as targets to regulate intraocular pressure.
Exp Eye Res
; 201: 108266, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32979397
14.
Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo.
Nat Chem Biol
; 14(12): 1099-1108, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420694
15.
An in vivo multiplexed small-molecule screening platform.
Nat Methods
; 13(10): 883-889, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27617390
16.
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.
Proc Natl Acad Sci U S A
; 113(1): 26-33, 2016 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668358
17.
Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model.
J Pharmacol Exp Ther
; 363(3): 394-401, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28970359
18.
Enrichment of O-GlcNAc-modified peptides using novel thiol-alkyne and thiol-disulfide exchange.
Bioorg Med Chem Lett
; 25(13): 2645-9, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25980911
19.
Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes.
bioRxiv
; 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38464067
20.
Pulmonary tumor thrombotic microangiopathy showing aggressive course after transurethral resection of urinary bladder: an autopsy case report.
Med Mol Morphol
; 45(4): 238-42, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23224604