Detalhe da pesquisa
1.
Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription.
Cell
; 155(6): 1351-64, 2013 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24290359
2.
MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.
Proc Natl Acad Sci U S A
; 114(20): E4048-E4056, 2017 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28461502
3.
NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model.
Neurobiol Dis
; 127: 390-397, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30928642
4.
Transnitrosylation of XIAP regulates caspase-dependent neuronal cell death.
Mol Cell
; 39(2): 184-95, 2010 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20670888
5.
S-Nitrosylation in neurogenesis and neuronal development.
Biochim Biophys Acta
; 1850(8): 1588-93, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25527866
6.
Aß induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.
Proc Natl Acad Sci U S A
; 110(27): E2518-27, 2013 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23776240
7.
ATM-dependent phosphorylation of MEF2D promotes neuronal survival after DNA damage.
J Neurosci
; 34(13): 4640-53, 2014 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24672010
8.
Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases.
Neurobiol Dis
; 84: 99-108, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25796565
9.
Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo.
Proc Natl Acad Sci U S A
; 105(27): 9397-402, 2008 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18599437
10.
Myocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cells.
J Neurosci
; 28(26): 6557-68, 2008 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18579729
11.
Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.
J Neurochem
; 104(4): 1116-31, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17995931
12.
Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency.
Invest Ophthalmol Vis Sci
; 58(9): 3741-3749, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28738418
13.
Transcriptional profiling of MEF2-regulated genes in human neural progenitor cells derived from embryonic stem cells.
Genom Data
; 3: 24-27, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25485232
14.
Effect of the ubiquitous transcription factors, SP1 and MAZ, on NMDA receptor subunit type 1 (NR1) expression during neuronal differentiation.
Brain Res Mol Brain Res
; 107(2): 89-96, 2002 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12425938
15.
Oligomeric Aß-induced synaptic dysfunction in Alzheimer's disease.
Mol Neurodegener
; 9: 48, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25394486
16.
S-nitrosylation-mediated redox transcriptional switch modulates neurogenesis and neuronal cell death.
Cell Rep
; 8(1): 217-28, 2014 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25001280
17.
Aberrant protein s-nitrosylation in neurodegenerative diseases.
Neuron
; 78(4): 596-614, 2013 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719160
18.
Isobaric tagging-based quantification by mass spectrometry of differentially regulated proteins in synaptosomes of HIV/gp120 transgenic mice: implications for HIV-associated neurodegeneration.
Exp Neurol
; 236(2): 298-306, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22575597
19.
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin.
Nat Med
; 15(12): 1407-13, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19915593
20.
HIV/gp120 decreases adult neural progenitor cell proliferation via checkpoint kinase-mediated cell-cycle withdrawal and G1 arrest.
Cell Stem Cell
; 1(2): 230-6, 2007 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18371353