Detalhe da pesquisa
1.
Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests.
Cell
; 185(19): 3603-3616.e13, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36084631
2.
Glucocorticoid receptor control of transcription: precision and plasticity via allostery.
Nat Rev Mol Cell Biol
; 18(3): 159-174, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28053348
3.
Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module.
Cell
; 159(1): 58-68, 2014 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25259920
4.
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
Nature
; 611(7937): 769-779, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385529
5.
Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Immunity
; 49(1): 42-55.e6, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30021146
6.
The structure, function and evolution of proteins that bind DNA and RNA.
Nat Rev Mol Cell Biol
; 15(11): 749-60, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25269475
7.
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.
Nucleic Acids Res
; 51(15): 7972-7987, 2023 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37395399
8.
Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators.
J Biol Chem
; 299(8): 104921, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37328104
9.
Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation.
Proc Natl Acad Sci U S A
; 118(30)2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34285072
10.
Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants.
J Clin Microbiol
; 61(10): e0013823, 2023 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37728336
11.
TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis.
PLoS Pathog
; 17(9): e1009941, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34559866
12.
Up-regulation of thioesterase superfamily member 2 in skeletal muscle promotes hepatic steatosis and insulin resistance in mice.
Hepatology
; 75(1): 154-169, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34433228
13.
Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.
Nat Chem Biol
; 17(3): 307-316, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33510451
14.
Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element.
Nucleic Acids Res
; 49(15): 8923-8933, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34289059
15.
A supergene-linked estrogen receptor drives alternative phenotypes in a polymorphic songbird.
Proc Natl Acad Sci U S A
; 117(35): 21673-21680, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817554
16.
Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment.
Proc Natl Acad Sci U S A
; 117(39): 24285-24293, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32917814
17.
Allosteric regulation of thioesterase superfamily member 1 by lipid sensor domain binding fatty acids and lysophosphatidylcholine.
Proc Natl Acad Sci U S A
; 117(36): 22080-22089, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32820071
18.
Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons.
J Biol Chem
; 296: 100024, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33410399
19.
Lactococcus lactis Subspecies cremoris Elicits Protection Against Metabolic Changes Induced by a Western-Style Diet.
Gastroenterology
; 159(2): 639-651.e5, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32169430
20.
Structural insights into glucocorticoid receptor function.
Biochem Soc Trans
; 49(5): 2333-2343, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34709368