Detalhe da pesquisa
1.
An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity.
Nat Chem Biol
; 20(1): 103-110, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37872402
2.
Repurposing plant hormone receptors as chemically-inducible genetic switches for dynamic regulation in yeast.
Metab Eng
; 83: 102-109, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38554744
3.
Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo.
Proc Natl Acad Sci U S A
; 118(38)2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34531324
4.
The MATH-BTB BPM3 and BPM5 subunits of Cullin3-RING E3 ubiquitin ligases target PP2CA and other clade A PP2Cs for degradation.
Proc Natl Acad Sci U S A
; 116(31): 15725-15734, 2019 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31308219
5.
A thermodynamic switch modulates abscisic acid receptor sensitivity.
EMBO J
; 41(7): e110799, 2022 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35373397
6.
Agrochemical control of plant water use using engineered abscisic acid receptors.
Nature
; 520(7548): 545-8, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25652827
7.
Optimized small-molecule pull-downs define MLBP1 as an acyl-lipid-binding protein.
Plant J
; 98(5): 928-941, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735592
8.
Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance.
Proc Natl Acad Sci U S A
; 110(29): 12132-7, 2013 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23818638
9.
A thermodynamic switch modulates abscisic acid receptor sensitivity.
EMBO J
; 30(20): 4171-84, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21847091
10.
In vitro reconstitution of an abscisic acid signalling pathway.
Nature
; 462(7273): 660-4, 2009 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19924127
11.
The abscisic acid receptor PYR1 in complex with abscisic acid.
Nature
; 462(7273): 665-8, 2009 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19898494
12.
A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors.
Nature
; 462(7273): 602-8, 2009 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19898420
13.
Potent and selective activation of abscisic acid receptors in vivo by mutational stabilization of their agonist-bound conformation.
Proc Natl Acad Sci U S A
; 108(51): 20838-43, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22139369
14.
Plant leucine aminopeptidases moonlight as molecular chaperones to alleviate stress-induced damage.
J Biol Chem
; 287(22): 18408-17, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22493451
15.
Modulation of abscisic acid signaling in vivo by an engineered receptor-insensitive protein phosphatase type 2C allele.
Plant Physiol
; 156(1): 106-16, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21357183
16.
Synthesis and characterization of abscisic acid receptor modulators.
Methods Enzymol
; 671: 435-470, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35878989
17.
Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds.
Nat Biotechnol
; 40(12): 1855-1861, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35726092
18.
PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis.
Plant J
; 61(2): 290-9, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19874541
19.
Modulation of drought resistance by the abscisic acid receptor PYL5 through inhibition of clade A PP2Cs.
Plant J
; 60(4): 575-88, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19624469
20.
Defining and Exploiting Hypersensitivity Hotspots to Facilitate Abscisic Acid Agonist Optimization.
ACS Chem Biol
; 14(3): 332-336, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30668093