Detalhe da pesquisa
1.
Influenza A virus polymerase acidic protein E23G/K substitutions weaken key baloxavir drug-binding contacts with minimal impact on replication and transmission.
PLoS Pathog
; 18(7): e1010698, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35830486
2.
Influenza A and B viruses with reduced baloxavir susceptibility display attenuated in vitro fitness but retain ferret transmissibility.
Proc Natl Acad Sci U S A
; 117(15): 8593-8601, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32217734
3.
Baloxavir Treatment Delays Influenza B Virus Transmission in Ferrets and Results in Limited Generation of Drug-Resistant Variants.
Antimicrob Agents Chemother
; 65(11): e0113721, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34424039
4.
Monoclonal Antibody Therapy Protects Pharmacologically Immunosuppressed Mice from Lethal Infection with Influenza B Virus.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631823
5.
Optimizing T-705 (favipiravir) treatment of severe influenza B virus infection in the immunocompromised mouse model.
J Antimicrob Chemother
; 74(5): 1333-1341, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30715325
6.
Growth and Pathogenic Potential of Naturally Selected Reassortants after Coinfection with Pandemic H1N1 and Highly Pathogenic Avian Influenza H5N1 Viruses.
J Virol
; 90(1): 616-23, 2016 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491154
7.
A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity In Vitro.
Antimicrob Agents Chemother
; 60(9): 5504-14, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27381402
8.
Profiling and characterization of influenza virus N1 strains potentially resistant to multiple neuraminidase inhibitors.
J Virol
; 89(1): 287-99, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25320319
9.
Avian Influenza A Viruses: Evolution and Zoonotic Infection.
Semin Respir Crit Care Med
; 37(4): 501-11, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27486732
10.
Development of a dual-protective live attenuated vaccine against H5N1 and H9N2 avian influenza viruses by modifying the NS1 gene.
Arch Virol
; 160(7): 1729-40, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25959557
11.
Virulence and transmissibility of H1N2 influenza virus in ferrets imply the continuing threat of triple-reassortant swine viruses.
Proc Natl Acad Sci U S A
; 109(39): 15900-5, 2012 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23019374
12.
Evaluation of heterosubtypic cross-protection against highly pathogenic H5N1 by active infection with human seasonal influenza A virus or trivalent inactivated vaccine immunization in ferret models.
J Gen Virol
; 95(Pt 4): 793-798, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24421115
13.
The homologous tripartite viral RNA polymerase of A/swine/Korea/CT1204/2009(H1N2) influenza virus synergistically drives efficient replication and promotes respiratory droplet transmission in ferrets.
J Virol
; 87(19): 10552-62, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23864624
14.
Early regulation of viral infection reduces inflammation and rescues mx-positive mice from lethal avian influenza infection.
Am J Pathol
; 182(4): 1308-21, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23395090
15.
Differential microRNA expression following infection with a mouse-adapted, highly virulent avian H5N2 virus.
BMC Microbiol
; 14: 252, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25266911
16.
Establishment of Vero cell RNA polymerase I-driven reverse genetics for Influenza A virus and its application for pandemic (H1N1) 2009 influenza virus vaccine production.
J Gen Virol
; 94(Pt 6): 1230-1235, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23486669
17.
Prokaryote-expressed M2e protein improves H9N2 influenza vaccine efficacy and protection against lethal influenza A virus in mice.
Virol J
; 10: 104, 2013 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23551908
18.
New insights into the neuraminidase-mediated hemagglutination activity of influenza A(H3N2) viruses.
Antiviral Res
; 218: 105719, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37717821
19.
Resistance profiles for the investigational neuraminidase inhibitor AV5080 in influenza A and B viruses.
Antiviral Res
; 217: 105701, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37567255
20.
Antiviral susceptibility of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses isolated from birds and mammals in the United States, 2022.
Antiviral Res
; 217: 105679, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37494978