Detalhe da pesquisa
1.
Enhanced brain-targeting and efficacy of cannabidiol via RVG-Exo/CBD nanodelivery system.
Biochem Biophys Res Commun
; 725: 150260, 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38878760
2.
Cannabidivarin alleviates α-synuclein aggregation via DAF-16 in Caenorhabditis elegans.
FASEB J
; 37(2): e22735, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36583706
3.
Cannabidiol alleviates neuroinflammation and attenuates neuropathic pain via targeting FKBP5.
Brain Behav Immun
; 111: 365-375, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37196785
4.
Exploring the trimerization process of a transmembrane helix with an ionizable residue by molecular dynamics simulations: a case study of transmembrane domain 5 of LMP-1.
Phys Chem Chem Phys
; 24(11): 7084-7092, 2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262149
5.
Artemisinin inhibits TLR4 signaling by targeting co-receptor MD2 in microglial BV-2 cells and prevents lipopolysaccharide-induced blood-brain barrier leakage in mice.
J Neurochem
; 157(3): 611-623, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33453127
6.
Stereochemistry and innate immune recognition: (+)-norbinaltorphimine targets myeloid differentiation protein 2 and inhibits toll-like receptor 4 signaling.
FASEB J
; 33(8): 9577-9587, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31162938
7.
Exploring Methamphetamine Nonenantioselectively Targeting Toll-like Receptor 4/Myeloid Differentiation Protein 2 by in Silico Simulations and Wet-Lab Techniques.
J Chem Inf Model
; 60(3): 1607-1613, 2020 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31935095
8.
Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain.
Brain Behav Immun
; 82: 432-444, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31542403
9.
Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response.
J Biol Chem
; 292(36): 15105-15120, 2017 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28673964
10.
Dissecting the Innate Immune Recognition of Opioid Inactive Isomer (+)-Naltrexone Derived Toll-like Receptor 4 (TLR4) Antagonists.
J Chem Inf Model
; 58(4): 816-825, 2018 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29518316
11.
Preparative Separation and Purification of Four Glycosides from Gentianae radix by High-Speed Counter-Current Chromatography and Comparison of Their Anti-NO Production Effects.
Molecules
; 22(11)2017 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29149084
12.
Transcriptome analysis of sika deer in China.
Mol Genet Genomics
; 291(5): 1941-53, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27423230
13.
GALNT12 promotes fibrosarcoma growth by accelerating YAP1 nuclear localization.
Oncol Lett
; 26(6): 543, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020290
14.
Cannabidiol Analogue CIAC001 for the Treatment of Morphine-Induced Addiction by Targeting PKM2.
J Med Chem
; 66(16): 11498-11516, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37531582
15.
ACT001 Inhibits TLR4 Signaling by Targeting Co-Receptor MD2 and Attenuates Neuropathic Pain.
Front Immunol
; 13: 873054, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35757727
16.
C. elegans as an in vivo model system for the phenotypic drug discovery for treating paraquat poisoning.
PeerJ
; 10: e12866, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35178301
17.
Cannabidiol protects against Alzheimer's disease in C. elegans via ROS scavenging activity of its phenolic hydroxyl groups.
Eur J Pharmacol
; 919: 174829, 2022 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35181336
18.
Velvet Antler Methanol Extracts Ameliorate Parkinson's Disease by Inhibiting Oxidative Stress and Neuroinflammation: From C. elegans to Mice.
Oxid Med Cell Longev
; 2021: 8864395, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33505591
19.
Dissecting Role of Charged Residue from Transmembrane Domain 5 of Latent Membrane Protein 1 via In Silico Simulations and Wet-Lab Experiments.
J Phys Chem B
; 125(8): 2124-2133, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33595309
20.
Engineered Exosomes-Based Photothermal Therapy with MRI/CT Imaging Guidance Enhances Anticancer Efficacy through Deep Tumor Nucleus Penetration.
Pharmaceutics
; 13(10)2021 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34683886