Detalhe da pesquisa
1.
Chronic intermittent hypoxia-induced cardiovascular and renal dysfunction: from adaptation to maladaptation.
J Physiol
; 601(24): 5553-5577, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37882783
2.
Control of Arterial Hypertension by the AhR Blocker CH-223191: A Chronopharmacological Study in Chronic Intermittent Hypoxia Conditions.
Adv Exp Med Biol
; 1427: 35-42, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37322333
3.
Cysteine as a Multifaceted Player in Kidney, the Cysteine-Related Thiolome and Its Implications for Precision Medicine.
Molecules
; 27(4)2022 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209204
4.
Cysteine metabolic circuitries: druggable targets in cancer.
Br J Cancer
; 124(5): 862-879, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33223534
5.
AHR canonical pathway: in vivo findings to support novel antihypertensive strategies.
Pharmacol Res
; 165: 105407, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33418029
6.
The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies.
Pharmacol Res
; 165: 105446, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515705
7.
A Mechanistic-Based and Non-invasive Approach to Quantify the Capability of Kidney to Detoxify Cysteine-Disulfides.
Adv Exp Med Biol
; 1306: 109-120, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33959909
8.
Anti-Angiogenic Therapy: Current Challenges and Future Perspectives.
Int J Mol Sci
; 22(7)2021 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33916438
9.
Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine.
Molecules
; 26(5)2021 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33802579
10.
First evidence of aryl hydrocarbon receptor as a druggable target in hypertension induced by chronic intermittent hypoxia.
Pharmacol Res
; 159: 104869, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32416216
11.
Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model.
Int J Mol Sci
; 21(11)2020 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32503263
12.
Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity.
Drug Metab Rev
; 51(1): 76-90, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30712401
13.
Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer.
BMC Evol Biol
; 18(1): 97, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29921232
14.
Usefulness of zebrafish larvae to evaluate drug-induced functional and morphological renal tubular alterations.
Arch Toxicol
; 92(1): 411-423, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28932931
15.
Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia.
Adv Exp Med Biol
; 1071: 83-88, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30357737
16.
Implications of sulfotransferase activity in interindividual variability in drug response: clinical perspective on current knowledge.
Drug Metab Rev
; 49(3): 357-371, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28554218
17.
Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.
Arch Toxicol
; 91(3): 1199-1211, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27417440
18.
HNF1ß drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC).
Tumour Biol
; 37(4): 4813-29, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26520442
19.
Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions.
J Antimicrob Chemother
; 69(2): 476-82, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24051761
20.
Fighting polymicrobial biofilms in bacterial vaginosis.
Microb Biotechnol
; 16(7): 1423-1437, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37042412