Detalhe da pesquisa
1.
Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window.
Genes Dev
; 23(17): 2088-101, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19723764
2.
Common variants in WFS1 confer risk of type 2 diabetes.
Nat Genet
; 39(8): 951-3, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17603484
3.
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance.
PLoS Biol
; 6(2): e37, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18288891
4.
Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice.
Cell Metab
; 2(2): 105-17, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16098828
5.
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol.
Hum Mol Genet
; 17(11): 1695-704, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18305138
6.
Genetic epidemiology of diabetes.
J Clin Invest
; 115(6): 1431-9, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15931378
7.
A global approach to identify differentially expressed genes in cDNA (two-color) microarray experiments.
Bioinformatics
; 23(16): 2073-9, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17550914
8.
Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.
Diabetes
; 55(6): 1581-91, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16731820
9.
Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells.
J Clin Invest
; 114(7): 928-36, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15467831
10.
Diabetes and insulin secretion: the ATP-sensitive K+ channel (K ATP) connection.
Diabetes
; 54(11): 3065-72, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16249427
11.
Endoplasmic reticulum stress-induced apoptosis is partly mediated by reduced insulin signaling through phosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase-3beta in mouse insulinoma cells.
Diabetes
; 54(4): 968-75, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15793234
12.
Activation of nuclear factor-kappaB by depolarization and Ca(2+) influx in MIN6 insulinoma cells.
Diabetes
; 51 Suppl 3: S484-8, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12475794
13.
Glucose and insulin treatment of insulinoma cells results in transcriptional regulation of a common set of genes.
Diabetes
; 53(6): 1496-508, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15161754
14.
A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.
Diabetes
; 53(4): 1134-40, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15047632
15.
Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population.
Diabetes
; 53(11): 3002-6, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15504983
16.
Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research.
Diabetes
; 51(7): 1997-2004, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12086925
17.
Transcriptional program of the endocrine pancreas in mice and humans.
Diabetes
; 52(7): 1604-10, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12829622
18.
Assessing allele frequencies of single nucleotide polymorphisms in DNA pools by pyrosequencing technology.
Biotechniques
; 32(5): 1144-6, 1148, 1150 passim, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12019788
19.
Phenotypic characteristics of early Wolfram syndrome.
Orphanet J Rare Dis
; 8: 64, 2013 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23981289
20.
Balance impairment in individuals with Wolfram syndrome.
Gait Posture
; 36(3): 619-24, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22771154