Detalhe da pesquisa
1.
Ubiquitin-proteasome pathway-mediated regulation of the Bcl-2 family: effects and therapeutic approaches.
Haematologica
; 109(1): 33-43, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37584295
2.
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88.
Nat Immunol
; 12(4): 344-51, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21358639
3.
Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
Nucleic Acids Res
; 48(22): 12727-12745, 2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33245769
4.
Cellular senescence: Silent operator and therapeutic target in cancer.
IUBMB Life
; 73(3): 530-542, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675120
5.
The anti-oxidant and pro-oxidant dichotomy of Bcl-2.
Biol Chem
; 397(7): 585-93, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27060742
6.
Ser70 phosphorylation of Bcl-2 by selective tyrosine nitration of PP2A-B56δ stabilizes its antiapoptotic activity.
Blood
; 124(14): 2223-34, 2014 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25082878
7.
A high-content phenotypic screen reveals the disruptive potency of quinacrine and 3',4'-dichlorobenzamil on the digestive vacuole of Plasmodium falciparum.
Antimicrob Agents Chemother
; 58(1): 550-8, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24217693
8.
Computational modelling of LY303511 and TRAIL-induced apoptosis suggests dynamic regulation of cFLIP.
Bioinformatics
; 29(3): 347-54, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23239672
9.
A novel MTORC2-AKT-ROS axis triggers mitofission and mitophagy-associated execution of colorectal cancer cells upon drug-induced activation of mutant KRAS.
Autophagy
; : 1-24, 2024 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38261660
10.
Pushing the Frontiers of Cancer Research: Highlights from the Frontiers in Cancer Science Conference 2023.
Cancer Res
; 84(8): 1195-1198, 2024 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38616656
11.
METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity.
Cell Death Dis
; 15(5): 338, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38744809
12.
The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity.
Blood
; 117(23): 6214-26, 2011 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21474673
13.
A superoxide-driven redox state promotes geroconversion and resistance to senolysis in replication-stress associated senescence.
Redox Biol
; 64: 102757, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37285741
14.
Therapeutic Potential of a Senolytic Approach in a Murine Model of Chronic GVHD.
Biology (Basel)
; 12(5)2023 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37237461
15.
Adipose-enriched peri-tumoral stroma, in contrast to myofibroblast-enriched stroma, prognosticates poorer survival in breast cancers.
NPJ Breast Cancer
; 9(1): 84, 2023 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863888
16.
Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies.
J Clin Invest
; 133(22)2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751299
17.
Recent advances in apoptosis, mitochondria and drug resistance in cancer cells.
Biochim Biophys Acta
; 1807(6): 735-45, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21453675
18.
Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2.
Biochem J
; 435(3): 545-51, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21486225
19.
Mitochondria-mediated oxidative stress during viral infection.
Trends Microbiol
; 30(7): 679-692, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35063304
20.
Identification of a novel catalytic inhibitor of topoisomerase II alpha that engages distinct mechanisms in p53wt or p53-/- cells to trigger G2/M arrest and senescence.
Cancer Lett
; 526: 284-303, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34843865