Detalhe da pesquisa
1.
Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity.
Nat Immunol
; 23(4): 568-580, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314846
2.
Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth.
Nat Immunol
; 20(3): 257-264, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30778250
3.
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Nat Immunol
; 20(10): 1299-1310, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31534238
4.
Structural basis for SHOC2 modulation of RAS signalling.
Nature
; 609(7926): 400-407, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35768504
5.
Application of N-Terminal Site-Specific Biotin and Digoxigenin Conjugates to Clinical Anti-drug Antibody Assay Development.
Bioconjug Chem
; 35(2): 174-186, 2024 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050929
6.
Optimized arylomycins are a new class of Gram-negative antibiotics.
Nature
; 561(7722): 189-194, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209367
7.
UniDec Processing Pipeline for Rapid Analysis of Biotherapeutic Mass Spectrometry Data.
Anal Chem
; 95(30): 11491-11498, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37478487
8.
High-Throughput, Quantitative Analysis of Peptide-Exchanged MHCI Complexes by Native Mass Spectrometry.
Anal Chem
; 94(42): 14593-14602, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179215
9.
High-Throughput Kinetic Characterization of Irreversible Covalent Inhibitors of KRASG12C by Intact Protein MS and Targeted MRM.
Anal Chem
; 94(2): 1230-1239, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990117
10.
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein.
J Am Chem Soc
; 143(28): 10571-10575, 2021 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34236858
11.
Dimerization Induced by C-Terminal 14-3-3 Binding Is Sufficient for BRAF Kinase Activation.
Biochemistry
; 59(41): 3982-3992, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32970425
12.
Quantitative Determination of Protein-Ligand Affinity by Size Exclusion Chromatography Directly Coupled to High-Resolution Native Mass Spectrometry.
Anal Chem
; 91(1): 903-911, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30481450
13.
Expression, purification, and characterization of recombinant human and murine milk fat globule-epidermal growth factor-factor 8.
Protein Expr Purif
; 124: 10-22, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102803
14.
Exposing the molecular heterogeneity of glycosylated biotherapeutics.
Nat Commun
; 15(1): 3259, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38627419
15.
Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms.
MAbs
; 14(1): 2135183, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36284469
16.
Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.
MAbs
; 13(1): 1893427, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33682619
17.
Data on charge separation of bispecific and mispaired IgGs using native charge-variant mass spectrometry.
Data Brief
; 30: 105435, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32274410
18.
Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization.
Nat Struct Mol Biol
; 27(2): 134-141, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31988522
19.
Targeted IgMs agonize ocular targets with extended vitreal exposure.
MAbs
; 12(1): 1818436, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32936727
20.
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.
Nat Commun
; 11(1): 6387, 2020 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318494