Detalhe da pesquisa
1.
Secretome of Cancer-Associated Fibroblasts (CAFs) Influences Drug Sensitivity in Cancer Cells.
J Proteome Res
; 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38767394
2.
Unbiased differential proteomic profiling between cancer-associated fibroblasts and cancer cell lines.
J Proteomics
; 288: 104973, 2023 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37481068
3.
Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence-Enabled Studies of Acute Phosphoproteomic Changes.
Mol Cancer Ther
; 21(6): 1020-1029, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35368084
4.
Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays.
Sci Rep
; 12(1): 18633, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36329085
5.
A phospho-proteomic study of cetuximab resistance in KRAS/NRAS/BRAFV600 wild-type colorectal cancer.
Cell Oncol (Dordr)
; 44(5): 1197-1206, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34462871
6.
Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease.
J Med Chem
; 62(5): 2447-2465, 2019 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30779566
7.
Developmental changes in ionotropic glutamate receptors: lessons from hippocampal synapses.
Neuroscientist
; 8(2): 143-53, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11954559
8.
The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design.
Oncotarget
; 4(10): 1647-61, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072592
9.
Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity.
J Med Chem
; 55(7): 3228-41, 2012 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22404346
10.
Preclinical pharmacology, antitumor activity, and development of pharmacodynamic markers for the novel, potent AKT inhibitor CCT128930.
Mol Cancer Ther
; 10(2): 360-71, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21191045
11.
Identification by high-throughput screening of viridin analogs as biochemical and cell-based inhibitors of the cell cycle-regulated nek2 kinase.
J Biomol Screen
; 15(8): 918-927, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20664067