Detalhe da pesquisa
1.
Antibiotics do not induce expression of acrAB directly but via a RamA-dependent pathway.
Antimicrob Agents Chemother
; 67(11): e0062023, 2023 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37815378
2.
Mapping direct and indirect MarA/SoxS/Rob/RamA regulons in Salmonella Typhimurium reveals repression of csgD and biofilm formation.
Microbiology (Reading)
; 169(5)2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37204124
3.
A Nonprofit Drug Development Model Is Part of the Antimicrobial Resistance (AMR) Solution.
Clin Infect Dis
; 74(10): 1866-1871, 2022 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34618892
4.
BSAC Vanguard Report Series: The future of drug development.
J Antimicrob Chemother
; 77(3): 543-544, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35195693
5.
Absence, loss-of-function, or inhibition of Escherichia coli AcrB does not increase expression of other efflux pump genes supporting the discovery of AcrB inhibitors as antibiotic adjuvants.
J Antimicrob Chemother
; 77(3): 633-640, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34897478
6.
EnvR is a potent repressor of acrAB transcription in Salmonella.
J Antimicrob Chemother
; 78(1): 133-140, 2022 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36308324
7.
Flomoxef and fosfomycin in combination for the treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance.
J Antimicrob Chemother
; 77(5): 1334-1343, 2022 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35170719
8.
The role of combination therapy in the treatment of severe infections caused by carbapenem resistant gram-negatives: a systematic review of clinical studies.
BMC Infect Dis
; 21(1): 545, 2021 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34107899
9.
Time dependent asymptotic analysis of the gene regulatory network of the AcrAB-TolC efflux pump system in gram-negative bacteria.
J Math Biol
; 82(4): 31, 2021 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33694073
10.
Overexpression of RamA, Which Regulates Production of the Multidrug Resistance Efflux Pump AcrAB-TolC, Increases Mutation Rate and Influences Drug Resistance Phenotype.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31988103
11.
The 2019 Garrod Lecture: MDR efflux in Gram-negative bacteria-how understanding resistance led to a new tool for drug discovery.
J Antimicrob Chemother
; 74(11): 3128-3134, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31626705
12.
Together towards a common goal: REVIVE, a community of antimicrobial researchers brought together by the Global Antibiotic Research & Development Partnership (GARDP).
J Antimicrob Chemother
; 74(7): 1769-1770, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30793751
13.
In vitro antimicrobial combination testing of and evolution of resistance to the first-in-class spiropyrimidinetrione zoliflodacin combined with six therapeutically relevant antimicrobials for Neisseria gonorrhoeae.
J Antimicrob Chemother
; 74(12): 3521-3529, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31730160
14.
Wastewater used for urban agriculture in West Africa as a reservoir for antibacterial resistance dissemination.
Environ Res
; 168: 14-24, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30253312
15.
CsrA maximizes expression of the AcrAB multidrug resistance transporter.
Nucleic Acids Res
; 45(22): 12798-12807, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29040729
16.
Discovery and development of new antibacterial drugs: learning from experience?
J Antimicrob Chemother
; 73(6): 1452-1459, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29438542
17.
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity.
Proc Natl Acad Sci U S A
; 112(11): 3511-6, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25737552
18.
Understanding the mechanisms and drivers of antimicrobial resistance.
Lancet
; 387(10014): 176-87, 2016 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26603922
19.
Quinolone-resistant gyrase mutants demonstrate decreased susceptibility to triclosan.
J Antimicrob Chemother
; 72(10): 2755-2763, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29091182
20.
Governing Global Antimicrobial Resistance: 6 Key Lessons From the Paris Climate Agreement.
Am J Public Health
; 112(4): 553-557, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35319963