Detalhe da pesquisa
1.
Granulocyte-macrophage colony-stimulating factor inactivation in CAR T-cells prevents monocyte-dependent release of key cytokine release syndrome mediators.
J Biol Chem
; 294(14): 5430-5437, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804212
2.
Modulation of chimeric antigen receptor surface expression by a small molecule switch.
BMC Biotechnol
; 19(1): 44, 2019 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31269942
3.
A Multidrug-resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy.
Mol Ther
; 23(9): 1507-18, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26061646
4.
Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.
Nucleic Acids Res
; 40(13): 6367-79, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22467209
5.
Characterization of three loci for homologous gene targeting and transgene expression.
Biotechnol Bioeng
; 110(8): 2225-35, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23475535
6.
Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy.
Front Immunol
; 14: 1172681, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37251405
7.
Preclinical Evidence of an Allogeneic Dual CD20xCD22 CAR to Target a Broad Spectrum of Patients with B-cell Malignancies.
Cancer Immunol Res
; 11(7): 946-961, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37257169
8.
Optimized two-step electroporation process to achieve efficient nonviral-mediated gene insertion into primary T cells.
FEBS Open Bio
; 12(1): 38-50, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34510816
9.
Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing.
Nat Commun
; 13(1): 3453, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773273
10.
Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model.
J Exp Med
; 198(10): 1527-37, 2003 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-14623908
11.
Straightforward Generation of Ultrapure Off-the-Shelf Allogeneic CAR-T Cells.
Front Bioeng Biotechnol
; 8: 678, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32671047
12.
Author Correction: Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality.
Nat Commun
; 11(1): 2357, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32382011
13.
Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA.
PLoS One
; 14(10): e0223775, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31618280
14.
Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality.
Nat Commun
; 10(1): 5100, 2019 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723132
15.
Développement des CAR-T dans les tumeurs solides.
Bull Cancer
; 105 Suppl 2: S178-S187, 2018 Dec.
Artigo
em Francês
| MEDLINE | ID: mdl-30686356
16.
A Versatile Safeguard for Chimeric Antigen Receptor T-Cell Immunotherapies.
Sci Rep
; 8(1): 8972, 2018 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29895885
17.
Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.
J Clin Invest
; 112(6): 902-14, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12975475
18.
Fine and Predictable Tuning of TALEN Gene Editing Targeting for Improved T Cell Adoptive Immunotherapy.
Mol Ther Nucleic Acids
; 9: 312-321, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29246309
19.
An oxygen sensitive self-decision making engineered CAR T-cell.
Sci Rep
; 7: 39833, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28106050
20.
Design of chimeric antigen receptors with integrated controllable transient functions.
Sci Rep
; 6: 18950, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26750734