Detalhe da pesquisa
1.
Mammalian life depends on two distinct pathways of DNA damage tolerance.
Proc Natl Acad Sci U S A
; 120(4): e2216055120, 2023 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669105
2.
Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.
Nature
; 572(7770): 538-542, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31367040
3.
Unraveling the molecular interactions between α7 nicotinic receptor and a RIC3 variant associated with backward speech.
Cell Mol Life Sci
; 81(1): 129, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38472514
4.
PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription.
Nucleic Acids Res
; 51(18): 9576-9593, 2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37070193
5.
Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells.
Cell Mol Life Sci
; 80(9): 249, 2023 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37578563
6.
The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation.
EMBO Rep
; 22(12): e52764, 2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661369
7.
Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites.
Nucleic Acids Res
; 49(7): 3856-3875, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33751115
8.
A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.
Nucleic Acids Res
; 47(18): 9557-9572, 2019 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31372638
9.
Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.
Mol Oncol
; 18(1): 156-169, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37854018
10.
The Tumor Coagulome as a Transcriptional Target and a Potential Effector of Glucocorticoids in Human Cancers.
Cancers (Basel)
; 15(5)2023 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36900323
11.
A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator.
bioRxiv
; 2023 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37333335
12.
Perturbations in 3D genome organization can promote acquired drug resistance.
Cell Rep
; 42(10): 113124, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37733591
13.
Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients.
medRxiv
; 2023 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865297
14.
Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.
EMBO Mol Med
; 15(12): e17737, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37902007
15.
Ribosome impairment regulates intestinal stem cell identity via ZAKÉ activation.
Nat Commun
; 13(1): 4492, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35918345
16.
Estrogen Receptor on the move: Cistromic plasticity and its implications in breast cancer.
Mol Aspects Med
; 78: 100939, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33358533
17.
Duality of glucocorticoid action in cancer: tumor-suppressor or oncogene?
Endocr Relat Cancer
; 28(6): R157-R171, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852423
18.
Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer.
Cancers (Basel)
; 13(24)2021 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34944934
19.
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.
Nat Commun
; 12(1): 4360, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34272384
20.
Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer.
Cancer Res
; 80(10): 1914-1926, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32193286