Detalhe da pesquisa
1.
Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy.
Nature
; 615(7953): 697-704, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890230
2.
IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing.
Proc Natl Acad Sci U S A
; 120(21): e2221116120, 2023 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37192158
3.
Reprogramming human T cell function and specificity with non-viral genome targeting.
Nature
; 559(7714): 405-409, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29995861
4.
Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules.
Proc Natl Acad Sci U S A
; 115(45): E10702-E10711, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348802
5.
Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma.
N Engl J Med
; 375(9): 819-29, 2016 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27433843
6.
A pRb-responsive, RGD-modified, and hyaluronidase-armed canine oncolytic adenovirus for application in veterinary oncology.
Mol Ther
; 22(5): 986-98, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24448161
7.
CAR-T cell manufacturing: Major process parameters and next-generation strategies.
J Exp Med
; 221(2)2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38226974
8.
CAR-T cell therapy targeting surface expression of TYRP1 to treat cutaneous and rare melanoma subtypes.
Nat Commun
; 15(1): 1244, 2024 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38336975
9.
Adenovirus i-leader truncation bioselected against cancer-associated fibroblasts to overcome tumor stromal barriers.
Mol Ther
; 20(1): 54-62, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21863000
10.
Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.
Sci Immunol
; 8(82): eabg2200, 2023 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37027480
11.
Remodeling of the tumor microenvironment through PAK4 inhibition sensitizes tumors to immune checkpoint blockade.
Cancer Res Commun
; 2(10): 1214-1228, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36588582
12.
Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti-PD-1 therapy.
J Clin Invest
; 131(12)2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33914706
13.
Precise T cell recognition programs designed by transcriptionally linking multiple receptors.
Science
; 370(6520): 1099-1104, 2020 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33243890
14.
PAK4 inhibition improves PD-1 blockade immunotherapy.
Nat Cancer
; 1(1): 46-58, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-34368780
15.
Overcoming Genetically Based Resistance Mechanisms to PD-1 Blockade.
Cancer Discov
; 10(8): 1140-1157, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32467343
16.
Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist.
Nat Commun
; 11(1): 660, 2020 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005809
17.
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.
Cancer Cell
; 38(4): 500-515.e3, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32916126
18.
Gene editing: Towards the third generation of adoptive T-cell transfer therapies.
Immunooncol Technol
; 1: 19-26, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35755321
19.
Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis.
Cell Discov
; 5: 62, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31798961
20.
IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System.
Clin Cancer Res
; 25(3): 1000-1011, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30409823