Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Is VITT really a HIT.

Ruggeri, Zaverio M; Ruf, Wolfram.

Nat Immunol ; 22(11): 1352-1353, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34686863

2.

Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling.

Zelaya, Hortensia; Grunz, Kristin; Nguyen, T Son; Habibi, Anxhela; Witzler, Claudius; Reyda, Sabine; Gonzalez-Menendez, Irene; Quintanilla-Martinez, Leticia; Bosmann, Markus; Weiler, Hartmut; Ruf, Wolfram.

Blood ; 143(10): 845-857, 2024 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-38096370

3.

Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development.

Müller-Calleja, Nadine; Grunz, Kristin; Nguyen, T Son; Posma, Jens; Pedrosa, Denise; Meineck, Myriam; Hollerbach, Anne; Braun, Johannes; Muth, Sabine; Schild, Hansjörg; Saar, Kathrin; Hübner, Norbert; Krishnaswamy, Sriram; Royce, Jennifer; Teyton, Luc; Lemmermann, Niels; Weinmann-Menke, Julia; Lackner, Karl J; Ruf, Wolfram.

Blood ; 143(12): 1167-1180, 2024 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-38142429

4.

Endothelial PTP1B Deletion Promotes VWF Exocytosis and Venous Thromboinflammation.

Zifkos, Konstantinos; Bochenek, Magdalena L; Gogiraju, Rajinikanth; Robert, Stéphane; Pedrosa, Denise; Kiouptsi, Klytaimnistra; Moiko, Kateryna; Wagner, Mathias; Mahfoud, Felix; Poncelet, Philippe; Münzel, Thomas; Ruf, Wolfram; Reinhardt, Christoph; Panicot-Dubois, Laurence; Dubois, Christophe; Schäfer, Katrin.

Circ Res ; 134(10): e93-e111, 2024 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-38563147

5.

Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFß1 and IL-27.

Riehl, Dennis R; Sharma, Arjun; Roewe, Julian; Murke, Florian; Ruppert, Clemens; Eming, Sabine A; Bopp, Tobias; Kleinert, Hartmut; Radsak, Markus P; Colucci, Giuseppe; Subramaniam, Saravanan; Reinhardt, Christoph; Giebel, Bernd; Prinz, Immo; Guenther, Andreas; Strand, Dennis; Gunzer, Matthias; Waisman, Ari; Ward, Peter A; Ruf, Wolfram; Schäfer, Katrin; Bosmann, Markus.

Proc Natl Acad Sci U S A ; 120(40): e2215421120, 2023 10 03.

Artigo em Inglês | MEDLINE | ID: mdl-37756334

6.

TF-FVIIa PAR2-ß-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice.

Kespohl, Meike; Goetzke, Carl Christoph; Althof, Nadine; Bredow, Clara; Kelm, Nicolas; Pinkert, Sandra; Bukur, Thomas; Bukur, Valesca; Grunz, Kristin; Kaur, Dilraj; Heuser, Arnd; Mülleder, Michael; Sauter, Martina; Klingel, Karin; Weiler, Hartmut; Berndt, Nikolaus; Gaida, Matthias M; Ruf, Wolfram; Beling, Antje.

Arterioscler Thromb Vasc Biol ; 44(4): 843-865, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38385286

7.

Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection.

Morodomi, Yosuke; Kanaji, Sachiko; Sullivan, Brian M; Zarpellon, Alessandro; Orje, Jennifer N; Won, Eric; Shapiro, Ryan; Yang, Xiang-Lei; Ruf, Wolfram; Schimmel, Paul; Ruggeri, Zaverio M; Kanaji, Taisuke.

Proc Natl Acad Sci U S A ; 119(48): e2212659119, 2022 11 29.

Artigo em Inglês | MEDLINE | ID: mdl-36409883

8.

Lipid-binding antiphospholipid antibodies: significance for pathophysiology and diagnosis of the antiphospholipid syndrome.

Müller-Calleja, Nadine; Ruf, Wolfram; Lackner, Karl J.

Crit Rev Clin Lab Sci ; : 1-18, 2024 Jan 31.

Artigo em Inglês | MEDLINE | ID: mdl-38293818

9.

Novel Tissue Factor Inhibition for Thromboprophylaxis in COVID-19: Primary Results of the ASPEN-COVID-19 Trial.

Hess, Connie N; Hsia, Judith; Carroll, Ian A; Nehler, Mark R; Ruf, Wolfram; Morrow, David A; Nicolau, Jose C; Berwanger, Otavio; Szarek, Michael; Capell, Warren H; Johri, Shilpa; Pursley, Michael S; Gupta, Ryan; Meehan, Patrick S; Franchi, Francesco; Effron, Mark B; Marshall, Debra; Graybill, Christopher A; Huebler, Sophia P; Keuer, Thomas; Bristow, Michael R; Bonaca, Marc P.

Arterioscler Thromb Vasc Biol ; 43(8): 1572-1582, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37381988

10.

Inflammatory Monocyte Counts Determine Venous Blood Clot Formation and Resolution.

Shahneh, Fatemeh; Christian Probst, Hans; Wiesmann, Sabine C; A-Gonzalez, Noelia; Ruf, Wolfram; Steinbrink, Kerstin; Raker, Verena K; Becker, Christian.

Arterioscler Thromb Vasc Biol ; 42(2): 145-155, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34911360

11.

Authors' reply to the Letter to the Editor: Tissue factor and its procoagulant activity on cancer-associated thromboembolism in pancreatic cancer.

Koizume, Shiro; Kobayashi, Satoshi; Ruf, Wolfram; Miyagi, Yohei.

Cancer Sci ; 113(5): 1888-1890, 2022 May.

Artigo em Inglês | MEDLINE | ID: mdl-35332617

12.

Metabolic and inflammatory reprogramming of macrophages by ONC201 translates in a pro-inflammatory environment even in presence of glioblastoma cells.

Geiß, Carsten; Witzler, Claudius; Poschet, Gernot; Ruf, Wolfram; Régnier-Vigouroux, Anne.

Eur J Immunol ; 51(5): 1246-1261, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33442873

13.

Rationale and design of a study to assess the safety and efficacy of rNAPc2 in COVID-19: the Phase 2b ASPEN-COVID-19 trial.

Hess, Connie N; Capell, Warren H; Bristow, Michael R; Ruf, Wolfram; Szarek, Michael; Morrow, David A; Nicolau, Jose C; Graybill, Christopher A; Marshall, Debra; Hsia, Judith; Bonaca, Marc P.

Am Heart J ; 246: 136-143, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-34986394

14.

Tissue factor and its procoagulant activity on cancer-associated thromboembolism in pancreatic cancer.

Kobayashi, Satoshi; Koizume, Shiro; Takahashi, Tomoko; Ueno, Makoto; Oishi, Ritsuko; Nagashima, Shuhei; Sano, Yusuke; Fukushima, Taito; Tezuka, Shun; Morimoto, Manabu; Nakamura, Sho; Narimatsu, Hiroto; Ruf, Wolfram; Miyagi, Yohei.

Cancer Sci ; 112(11): 4679-4691, 2021 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-34382298

15.

Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis.

Müller-Calleja, Nadine; Hollerbach, Anne; Ritter, Svenja; Pedrosa, Denise G; Strand, Dennis; Graf, Claudine; Reinhardt, Christoph; Strand, Susanne; Poncelet, Philippe; Griffin, John H; Lackner, Karl J; Ruf, Wolfram.

Blood ; 134(14): 1119-1131, 2019 10 03.

Artigo em Inglês | MEDLINE | ID: mdl-31434703

16.

Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension.

Helmstädter, Johanna; Frenis, Katie; Filippou, Konstantina; Grill, Alexandra; Dib, Mobin; Kalinovic, Sanela; Pawelke, Franziska; Kus, Kamil; Kröller-Schön, Swenja; Oelze, Matthias; Chlopicki, Stefan; Schuppan, Detlef; Wenzel, Philip; Ruf, Wolfram; Drucker, Daniel J; Münzel, Thomas; Daiber, Andreas; Steven, Sebastian.

Arterioscler Thromb Vasc Biol ; 40(1): 145-158, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31747801

17.

Roles of factor Xa beyond coagulation.

Ruf, Wolfram.

J Thromb Thrombolysis ; 52(2): 391-396, 2021 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-33893900

18.

Podocyte Integrin-ß₃ and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy.

Madhusudhan, Thati; Ghosh, Sanchita; Wang, Hongjie; Dong, Wei; Gupta, Dheerendra; Elwakiel, Ahmed; Stoyanov, Stoyan; Al-Dabet, Moh'd Mohanad; Krishnan, Shruthi; Biemann, Ronald; Nazir, Sumra; Zimmermann, Silke; Mathew, Akash; Gadi, Ihsan; Rana, Rajiv; Zeng-Brouwers, Jinyang; Moeller, Marcus J; Schaefer, Liliana; Esmon, Charles T; Kohli, Shrey; Reiser, Jochen; Rezaie, Alireza R; Ruf, Wolfram; Isermann, Berend.

J Am Soc Nephrol ; 31(8): 1762-1780, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32709711

19.

Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes.

Kyselova, Anastasia; Elgheznawy, Amro; Wittig, Ilka; Heidler, Juliana; Mann, Alexander W; Ruf, Wolfram; Fleming, Ingrid; Randriamboavonjy, Voahanginirina.

Basic Res Cardiol ; 115(6): 75, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33258989

20.

Extravascular coagulation in hematopoietic stem and progenitor cell regulation.

Nguyen, T Son; Lapidot, Tsvee; Ruf, Wolfram.

Blood ; 132(2): 123-131, 2018 07 12.

Artigo em Inglês | MEDLINE | ID: mdl-29866813

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