Detalhe da pesquisa
1.
The Purinergic Receptor P2X4 Promotes Th17 Activation and the Development of Arthritis.
J Immunol
; 208(5): 1115-1127, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35165166
2.
Epidermal melanocytes metabolize extracellular nucleotides by purinergic enzymes.
Biochem Cell Biol
; 101(3): 259-266, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36657128
3.
Preclinical evaluation of bozepinib in bladder cancer cell lines: modulation of the NPP1 enzyme.
Purinergic Signal
; 2023 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37906424
4.
Synthesis and structure-activity relationships of ticlopidine derivatives and analogs as inhibitors of ectonucleotidase CD39.
Bioorg Chem
; 135: 106460, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37023582
5.
Exploring chromone sulfonamides and sulfonylhydrazones as highly selective ectonucleotidase inhibitors: Synthesis, biological evaluation and in silico study.
Bioorg Chem
; 134: 106450, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36924652
6.
NTPDase1/CD39 Ectonucleotidase Is Necessary for Normal Arterial Diameter Adaptation to Flow.
Int J Mol Sci
; 24(20)2023 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37894719
7.
NTPDase8 protects mice from intestinal inflammation by limiting P2Y6 receptor activation: identification of a new pathway of inflammation for the potential treatment of IBD.
Gut
; 71(1): 43-54, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33452178
8.
Antenatal Dexamethasone Treatment Induces Sex-dependent Upregulation of NTPDase1/CD39 and Ecto-5'-nucleotidase/CD73 in the Rat Fetal Brain.
Cell Mol Neurobiol
; 42(6): 1965-1981, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761054
9.
Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y6 receptor antagonists.
Bioorg Med Chem Lett
; 75: 128981, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36089113
10.
Synthesis, characterization and biological evaluation of thiadiazole amide derivatives as nucleoside triphosphate diphosphohydrolases (NTPDases) inhibitors.
Bioorg Chem
; 118: 105456, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34800887
11.
Identification of thienopyrimidine glycinates as selective inhibitors for h-NTPDases.
Bioorg Chem
; 129: 106196, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36279741
12.
Neutrophils: fast and furious-the nucleotide pathway.
Purinergic Signal
; 17(3): 371-383, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33913070
13.
Influence of NSAIDs and methotrexate on CD73 expression and glioma cell growth.
Purinergic Signal
; 17(2): 273-284, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33745072
14.
Extracellular ectonucleotidases are differentially regulated in murine tissues and human polymorphonuclear leukocytes during sepsis and inflammation.
Purinergic Signal
; 17(4): 713-724, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34604944
15.
Synthesis, In-vitro evaluation and molecular docking studies of oxoindolin phenylhydrazine carboxamides as potent and selective inhibitors of ectonucleoside triphosphate diphosphohydrolase (NTPDase).
Bioorg Chem
; 112: 104957, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34020240
16.
Divergent synthesis and elaboration of structure activity relationship for quinoline derivatives as highly selective NTPDase inhibitor.
Bioorg Chem
; 115: 105240, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34416508
17.
Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39.
Mar Drugs
; 19(2)2021 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33499103
18.
2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors.
Arch Pharm (Weinheim)
; 354(12): e2100300, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34697820
19.
Imatinib mesylate affects extracellular ATP catabolism and expression of NTPDases in a chronic myeloid leukemia cell line.
Purinergic Signal
; 16(1): 29-40, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31955347
20.
Structural investigation on thiazolo[5,4-d]pyrimidines to obtain dual-acting blockers of CD73 and adenosine A2A receptor as potential antitumor agents.
Bioorg Med Chem Lett
; 30(9): 127067, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32165041