Detalhe da pesquisa
1.
A phase I study of pevonedistat, azacitidine, and venetoclax in patients with relapsed/refractory acute myeloid leukemia.
Haematologica
; 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38572562
2.
Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells.
Genes Dev
; 29(20): 2140-52, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494789
3.
Correction: High cell surface death receptor expression determines type I versus type II signaling.
J Biol Chem
; 298(5): 101980, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35490622
4.
4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells.
Blood
; 127(22): 2711-22, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26917778
5.
Immunodetection of human topoisomerase I-DNA covalent complexes.
Nucleic Acids Res
; 44(6): 2816-26, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26917015
6.
BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma.
Blood
; 125(4): 658-67, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25452615
7.
Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression.
J Biol Chem
; 289(30): 20543-58, 2014 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895135
8.
Context-dependent antagonism between Akt inhibitors and topoisomerase poisons.
Mol Pharmacol
; 85(5): 723-34, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24569089
9.
CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak.
J Biol Chem
; 288(32): 22899-914, 2013 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23798675
10.
Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies.
Blood
; 119(2): 476-87, 2012 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22080480
11.
Farnesyltransferase inhibitor tipifarnib inhibits Rheb prenylation and stabilizes Bax in acute myelogenous leukemia cells.
Haematologica
; 99(1): 60-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23996484
12.
AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death.
Cell Death Differ
; 31(4): 405-416, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38538744
13.
Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes.
J Biol Chem
; 287(6): 4198-210, 2012 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22158865
14.
Cytotoxicity of farnesyltransferase inhibitors in lymphoid cells mediated by MAPK pathway inhibition and Bim up-regulation.
Blood
; 118(18): 4872-81, 2011 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21673341
15.
Multi-institutional phase 2 study of the farnesyltransferase inhibitor tipifarnib (R115777) in patients with relapsed and refractory lymphomas.
Blood
; 118(18): 4882-9, 2011 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21725056
16.
Active vaccination with vaccinia virus A33 protects mice against lethal vaccinia and ectromelia viruses but not against cowpoxvirus; elucidation of the specific adaptive immune response.
Virol J
; 10: 229, 2013 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23842430
17.
Establishing Infodemic Management in Germany: A Framework for Social Listening and Integrated Analysis to Report Infodemic Insights at the National Public Health Institute.
JMIR Infodemiology
; 3: e43646, 2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37261891
18.
A phase 2 and pharmacological study of sapanisertib in patients with relapsed and/or refractory acute lymphoblastic leukemia.
Cancer Med
; 12(23): 21229-21239, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37960985
19.
Relationship between BCL2 mutations and follicular lymphoma outcome in the chemoimmunotherapy era.
Blood Cancer J
; 13(1): 81, 2023 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37193683
20.
High cell surface death receptor expression determines type I versus type II signaling.
J Biol Chem
; 286(41): 35823-35833, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21865165