Detalhe da pesquisa
1.
O6-methylguanine-induced transcriptional mutagenesis reduces p53 tumor-suppressor function.
Proc Natl Acad Sci U S A
; 115(18): 4731-4736, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29666243
2.
Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair.
Nucleic Acids Res
; 46(7): 3498-3516, 2018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29474673
3.
The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro.
Biochemistry
; 56(24): 3008-3018, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28514164
4.
Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription.
J Biol Chem
; 291(2): 848-61, 2016 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26559971
5.
O6-methylguanine induces altered proteins at the level of transcription in human cells.
Nucleic Acids Res
; 38(22): 8178-87, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20702424
6.
Benzo[a]pyrene diol epoxide stimulates an inflammatory response in normal human lung fibroblasts through a p53 and JNK mediated pathway.
Carcinogenesis
; 31(6): 1149-57, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20382639
7.
Transcription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase.
Nucleic Acids Res
; 36(20): 6459-71, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18854351
8.
Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase.
DNA Repair (Amst)
; 7(8): 1276-88, 2008 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18555749
9.
Construction and purification of site-specifically modified DNA templates for transcription assays.
Nucleic Acids Res
; 31(7): e40, 2003 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12655028
10.
Human RNA polymerase II is partially blocked by DNA adducts derived from tumorigenic benzo[c]phenanthrene diol epoxides: relating biological consequences to conformational preferences.
Nucleic Acids Res
; 31(20): 6004-15, 2003 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14530448
11.
Transcription and DNA adducts: what happens when the message gets cut off?
DNA Repair (Amst)
; 3(12): 1537-48, 2004 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15474416
12.
Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.
DNA Repair (Amst)
; 1(8): 683-96, 2002 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-12509290
13.
DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
J Mol Biol
; 321(1): 29-47, 2002 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12139931
14.
Transcription past DNA adducts derived from polycyclic aromatic hydrocarbons.
Mutat Res
; 577(1-2): 146-54, 2005 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15922365
15.
Transcription processing at 1,N2-ethenoguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase.
J Mol Biol
; 375(2): 353-66, 2008 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18022639
16.
Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase.
J Biol Chem
; 282(2): 1397-408, 2007 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17090533
17.
The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function relationship through experimental and computational approaches.
J Biol Chem
; 279(35): 36951-61, 2004 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-15210693