Detalhe da pesquisa
1.
Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease.
Pharm Res
; 40(11): 2597-2606, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37704895
2.
Predicting Maternal-Fetal Disposition of Fentanyl Following Intravenous and Epidural Administration Using Physiologically Based Pharmacokinetic Modeling.
Drug Metab Dispos
; 49(11): 1003-1015, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34407992
3.
Influence of St. John's Wort on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics, and Clinical Effects: A Randomized Clinical Trial.
Anesthesiology
; 132(3): 491-503, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794512
4.
Novel Long-Acting Drug Combination Nanoparticles Composed of Gemcitabine and Paclitaxel Enhance Localization of Both Drugs in Metastatic Breast Cancer Nodules.
Pharm Res
; 37(10): 197, 2020 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32968837
5.
Recommended Approaches for Pharmacokinetic Natural Product-Drug Interaction Research: a NaPDI Center Commentary.
Drug Metab Dispos
; 46(7): 1041-1045, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735755
6.
Disposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 in Tissue-Selective Accumulation of Para-Hydroxymethamphetamine.
Drug Metab Dispos
; 46(9): 1277-1284, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29915156
7.
Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation.
Drug Metab Dispos
; 46(2): 100-108, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29158248
8.
Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation.
Drug Metab Dispos
; 46(5): 552-560, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467215
9.
Selection of Priority Natural Products for Evaluation as Potential Precipitants of Natural Product-Drug Interactions: A NaPDI Center Recommended Approach.
Drug Metab Dispos
; 46(7): 1046-1052, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735752
10.
Effect of Coenzyme Q10 on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ10 Biomarker Trial.
Am J Kidney Dis
; 69(3): 389-399, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27927588
11.
P-gp/ABCB1 exerts differential impacts on brain and fetal exposure to norbuprenorphine.
Pharmacol Res
; 119: 61-71, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28111265
12.
Development of a microphysiological model of human kidney proximal tubule function.
Kidney Int
; 90(3): 627-37, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27521113
13.
Dexmedetomidine reduces cranial temperature in hypothermic neonatal rats.
Pediatr Res
; 77(6): 772-8, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25751572
14.
Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress.
BMC Nephrol
; 16: 183, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26531095
15.
Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport.
Kidney Int
; 85(3): 522-8, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24132209
16.
Maternal-fetal disposition of glyburide in pregnant mice is dependent on gestational age.
J Pharmacol Exp Ther
; 350(2): 425-34, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24898265
17.
Aspirin use and knowledge in the community: a population- and health facility based survey for measuring local health system performance.
BMC Cardiovasc Disord
; 14: 16, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24507089
18.
Physiologically based Pharmacokinetic Model Validated to Enable Predictions Of Multiple Drugs in a Long-acting Drug-combination Nano-Particles (DcNP): Confirmation with 3 HIV Drugs, Lopinavir, Ritonavir, and Tenofovir in DcNP Products.
J Pharm Sci
; 113(6): 1653-1663, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38382809
19.
Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo.
Toxicol Appl Pharmacol
; 266(1): 122-31, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23153560
20.
Tacrolimus placental transfer at delivery and neonatal exposure through breast milk.
Br J Clin Pharmacol
; 76(6): 988-96, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23528073