Detalhe da pesquisa
1.
Conserved class B GPCR activation by a biased intracellular agonist.
Nature
; 621(7979): 635-641, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524305
2.
Synergistic Effects of PtRhNiFeCu High Entropy Alloy Nanocatalyst for Hydrogen Evolution and Oxygen Reduction Reactions.
Small
; : e2309819, 2024 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229574
3.
A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency.
Bioorg Med Chem
; 107: 117761, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38795571
4.
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD.
Bioorg Med Chem
; 96: 117511, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37976806
5.
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis.
Acta Pharmacol Sin
; 44(8): 1649-1664, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-36997665
6.
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice.
Acta Pharmacol Sin
; 44(3): 596-609, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36085523
7.
Challenging the Status Quo: Debunking the Necessity of 5-Year to 10-Year Patient-Reported Outcome Measures in Total Hip and Knee Arthroplasties.
J Arthroplasty
; 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38122838
8.
Cu Single-Atom Catalysts for High-Selectivity Electrocatalytic Acetylene Semihydrogenation.
Angew Chem Int Ed Engl
; 62(33): e202307848, 2023 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37378584
9.
Stable Bismuth-Doped Lead Halide Perovskite Core-Shell Nanocrystals by Surface Segregation Effect.
Small
; 18(3): e2104399, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34837312
10.
Discovery of pyrroledione analogs as potent transient receptor potential canonical channel 5 inhibitors.
Bioorg Med Chem Lett
; 61: 128612, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143983
11.
Synthesis of AC1903 analogs as potent transient receptor potential canonical channel 4/5 inhibitors and biological evaluation.
Bioorg Med Chem
; 68: 116853, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35653869
12.
Modification of pore-wall in direct ink writing wollastonite scaffolds favorable for tuning biodegradation and mechanical stability and enhancing osteogenic capability.
FASEB J
; 34(4): 5673-5687, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32115776
13.
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio.
Bioorg Med Chem
; 43: 116280, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34256254
14.
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice.
Acta Pharmacol Sin
; 42(11): 1834-1846, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33574568
15.
Lipoprotein-associated phospholipase A2: The story continues.
Med Res Rev
; 40(1): 79-134, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31140638
16.
Quantification of microbiota-related phenols and aromatic acids in mouse feces of a diabetic nephropathy model by simultaneous BDAPE derivatization using ultra-performance liquid chromatography-tandem mass spectrometry.
Anal Bioanal Chem
; 412(13): 3241-3252, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342129
17.
Fate and transfer of heavy metals following repeated biogas slurry application in a rice-wheat crop rotation.
J Environ Manage
; 270: 110938, 2020 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32721356
18.
Functional Metabolomics Characterizes a Key Role for N-Acetylneuraminic Acid in Coronary Artery Diseases.
Circulation
; 137(13): 1374-1390, 2018 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29212895
19.
Can men with atrial fibrillation really rest easy with a CHA2DS2-VASc score of 0?
BMC Cardiovasc Disord
; 19(1): 178, 2019 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31349811
20.
Magnesium lithospermate B improves the gut microbiome and bile acid metabolic profiles in a mouse model of diabetic nephropathy.
Acta Pharmacol Sin
; 40(4): 507-513, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941869