Detalhe da pesquisa
1.
Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs.
Bioinformatics
; 39(1)2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36472455
2.
Using What We Already Have: Uncovering New Drug Repurposing Strategies in Existing Omics Data.
Annu Rev Pharmacol Toxicol
; 60: 333-352, 2020 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31337270
3.
PheWAS-ME: a web-app for interactive exploration of multimorbidity patterns in PheWAS.
Bioinformatics
; 37(12): 1778-1780, 2021 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33051675
4.
A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection.
Infect Immun
; 87(5)2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30782860
5.
Repurposing N-acetylcysteine for management of non-acetaminophen induced acute liver failure: an evidence scan from a global health perspective.
Transl Gastroenterol Hepatol
; 9: 2, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38317753
6.
The Astounding Breadth of Health Disparity: Phenome-Wide Effects of Race on Disease Risk.
J Natl Med Assoc
; 113(2): 187-194, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32958289
7.
Human and Machine Intelligence Together Drive Drug Repurposing in Rare Diseases.
Front Genet
; 12: 707836, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34394194
8.
Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use.
Drug Saf
; 43(6): 567-582, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32112228
9.
Systematically Prioritizing Candidates in Genome-Based Drug Repurposing.
Assay Drug Dev Technol
; 17(8): 352-363, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31769998
10.
Using Human 'Experiments of Nature' to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors.
Drug Saf
; 41(3): 303-311, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29185237
11.
Mining 100 million notes to find homelessness and adverse childhood experiences: 2 case studies of rare and severe social determinants of health in electronic health records.
J Am Med Inform Assoc
; 25(1): 61-71, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29016793
12.
Motivation for Launching a Cancer Metastasis Inhibition (CMI) Program.
Target Oncol
; 13(1): 61-68, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29218624
13.
When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data.
Assay Drug Dev Technol
; 15(8): 354-361, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29193979
14.
Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.
Assay Drug Dev Technol
; 15(3): 113-119, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379727
15.
Reply to Ward and Colleagues' Comment on "Using Human Experiments of Nature to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors".
Drug Saf
; 41(11): 1101, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30066313
16.
Advocating for mutually beneficial access to shelved compounds.
Future Med Chem
; 10(12): 1395-1398, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29788759
17.
Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome.
Dis Model Mech
; 6(4): 1001-11, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23580201