Detalhe da pesquisa
1.
Exploring the role of ex vivo metabolism on blood and plasma measurements of oxytocin among women in the third stage of labour: A post hoc study.
Br J Clin Pharmacol
; 89(12): 3669-3680, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37522415
2.
Pharmacokinetics and safety of inhaled oxytocin compared with intramuscular oxytocin in women in the third stage of labour: A randomized open-label study.
Br J Clin Pharmacol
; 89(12): 3681-3689, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37485589
3.
A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvß6 integrin inhibitor.
Respir Res
; 21(1): 75, 2020 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32216814
4.
A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome.
Crit Care
; 21(1): 234, 2017 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28877748
5.
Effects of a novel sodium channel blocker, GSK2339345, in patients with refractory chronic coughâ©.
Int J Clin Pharmacol Ther
; 55(9): 712-719, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28679467
6.
Population pharmacokinetics of inhaled fluticasone furoate and vilanterol in adult and adolescent patients with asthma.
Int J Clin Pharmacol Ther
; 54(4): 269-81, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26902504
7.
Metabolism and disposition of vilanterol, a long-acting ß(2)-adrenoceptor agonist for inhalation use in humans.
Drug Metab Dispos
; 41(1): 89-100, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23043183
8.
Vilanterol trifenatate, a novel inhaled long-acting beta2 adrenoceptor agonist, is well tolerated in healthy subjects and demonstrates prolonged bronchodilation in subjects with asthma and COPD.
Pulm Pharmacol Ther
; 26(2): 256-64, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23232038
9.
An open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single doses of GSK2586881 in participants with pulmonary arterial hypertension.
Pulm Circ
; 12(1): e12024, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-35506108
10.
Effects of Recombinant Human Angiotensin-Converting Enzyme 2 on Response to Acute Hypoxia and Exercise: A Randomised, Placebo-Controlled Study.
Pulm Ther
; 7(2): 487-501, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34189703
11.
Safety, Tolerability and Pharmacokinetics of Single Doses of Oxytocin Administered via an Inhaled Route in Healthy Females: Randomized, Single-blind, Phase 1 Study.
EBioMedicine
; 22: 249-255, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28781129
12.
Clinical pharmacology of Cilomilast.
Clin Pharmacokinet
; 45(3): 217-33, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16509757
13.
Population Pharmacokinetics of Inhaled Fluticasone Furoate and Vilanterol in Subjects with Chronic Obstructive Pulmonary Disease.
Eur J Drug Metab Pharmacokinet
; 41(6): 743-758, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26474864
14.
Effect of once-daily fluticasone furoate/vilanterol on 24-hour pulmonary function in patients with chronic obstructive pulmonary disease: a randomized, three-way, incomplete block, crossover study.
Clin Ther
; 34(8): 1655-66.e5, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22789766